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Merck
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Key Documents

SAB5700329

Sigma-Aldrich

Anti-Phospho-γH2A.X-S139 antibody produced in rabbit

别名:

γH2AX, H2A.X, H2A/X, H2AFX, H2AX, Histone H2AX, gamma H2A.X, histone H2AX

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

15

物種活性

rat, mouse, human

濃度

0.34 mg/ml

技術

immunofluorescence: 1:50-1:100
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pSer139)

基因資訊

human ... H2AFX(3014)

一般說明

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

免疫原

A synthetic phosphorylated peptide around S139 of human γH2A.X (NP_002096.1).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20°C. Avoid freeze / thaw cycles.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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