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生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
分子量
41 kDa
物種活性
human, rat, mouse
濃度
1 mg/mL
技術
ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NKX2-1(7080)
一般說明
NK2 homeobox 1 (NKX2-1) is expressed in epithelial cells of the thyroid gland and lungs. The gene encoding NKX2-1 is localized on human chromosome 14q13.
免疫原
Antibody was raised against a 16 amino acid peptide near the amino terminus of human NKX2-1.
生化／生理作用
NK2 homeobox 1(NKX2-1) has a role in the development of thyroid glands, lungs and brain. It modulates gene expression during embryogenesis. NKX2-1 has been found to be expressed in adenocarcinoma and small cell lung cancer. This protein acts as an immunohistological marker to distinguish between primary lung carcinoma and non-pulmonary cancer.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
聯結
The action of this antibody can be blocked using blocking peptide SBP3500757.
外觀
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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相關產品
儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Distinct expression of NK2 homeobox 1 (NKX2-1) and goblet cell hyperplasia in nasal polyps with different endotypes.
Du J, et al.
International Forum of Allergy & Rhinology, 7(7) (2017)
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas.
Klingen T A, et al.
Diagnostic Pathology, 8(1), 80-80 (2013)
Recurrent drop attacks in early childhood as presenting symptom of benign hereditary chorea caused by TITF1 gene mutations.
Rosati A, et al.
Developmental Medicine and Child Neurology, 57(8), 777-779 (2015)
Benign hereditary chorea related to NKX2. 1: expansion of the genotypic and phenotypic spectrum.
Peall K J, et al.
Developmental Medicine and Child Neurology, 56(7), 642-648 (2014)
Value of thyroid transcription factor (TTF)-1 for diagnosis and prognosis of patients with locally advanced or metastatic small cell lung cancer.
Misch D, et al.
Diagnostic Pathology, 10(1), 21-21 (2015)
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