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Merck

S4447

Sigma-Aldrich

α-Synuclein E46K 人

recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder

别名:

NACP (Non-a-beta component of Alzheimer disease amyloid, precursor), PARK1, PARK4, PD1, non A4 component of amyloid precursor

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

重組細胞

expressed in E. coli

品質等級

化驗

≥90% (SDS-PAGE)

形狀

lyophilized powder

分子量

apparent mol wt 19-20 kDa

UniProt登錄號

相容性

for use with ABI StepOnePlus

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... SNCA(6622)

生化/生理作用

Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A tran­sition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein.
Deposition of α-synuclein as fibrillary tangles is a hallmark of certain neurodegenerative diseases including Parkinson′s. Among the familial mutations of α-synuclein, E46K has the greatest potential to aggregate.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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