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Merck
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Key Documents

RAB0278

Sigma-Aldrich

Rat IL-1 β ELISA Kit

for cell and tissue lysates

别名:

Il-1 beta, Interleukin-1 beta

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

rat

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 68.59-50000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

rat ... Il1b(24494)

一般說明

The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.

免疫原

Recombinant Rat IL-1 β

應用

For research use only. Not for use in diagnostic procedures

Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

生化/生理作用

Pro-inflammatory cytokine IL-1 Β (IL1B), which is highly expressed on Β-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1Β and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1Β enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1Β plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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产品编号
说明
化学品安全说明书

  • RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)化学品安全说明书

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)化学品安全说明书

  • RABLYSIS12X Cell Lysis Buffer (Item J)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials


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Interleukin-1? promotes the neurogenesis of carotid bodies by stimulating the activation of ERK1/2.
Xue F
Respiratory Physiology & Neurobiology null
Proinflammatory cytokine interleukin-1? suppresses cold-induced thermogenesis in adipocytes.
Goto T
Cytokine null
Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy.
Ahmed S
Inflammation null
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1?.
Ilyas G
Journal of Hepatology null
Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-?B signaling pathway.
Wang YL
Molecular Medicine Reports null

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