所有图片(2)
About This Item
经验公式（希尔记法）:
C8H12N4O5
CAS号:
分子量:
244.20
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77
推荐产品
品質等級
化驗
≥98% (TLC)
形狀
powder
溶解度
water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
抗生素活性譜
viruses
作用方式
DNA synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
InChI
1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI 密鑰
IWUCXVSUMQZMFG-AFCXAGJDSA-N
基因資訊
human ... IMPDH1(3614) , IMPDH2(3615)
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一般說明
化学结构：核苷
嘌呤核苷酸生物合成中咪唑核苷酸中间体的类似物。
生化／生理作用
用于抵御多种人类病毒感染的抗病毒剂，特别是慢性肝炎C、HIV 和腺病毒。其代谢产物利巴韦林 5′-磷酸，是肌苷一磷酸 (IMP) 脱氢酶的抑制剂，但也有实验证据支持许多其他作用机制。
抗病毒剂。其代谢产物利巴韦林 5′-磷酸，是肌苷一磷酸 (IMP) 脱氢酶的抑制剂。用于抑制嘌呤（GTP 池）在肌苷单磷酸 (IMP) 脱氢酶级别的生物合成，并作为抑制病毒RNA依赖性RNA聚合酶的二磷酸和三磷酸的前体。
訊號詞
Danger
危險聲明
危險分類
Muta. 2 - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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