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Merck
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文件

P8511

Sigma-Aldrich

反式 -2-苯环丙胺 盐酸盐

别名:

反苯环丙胺

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About This Item

线性分子式:
C6H5C3H4NH2·HCl
CAS号:
1986-47-6
分子量:
169.65
MDL號碼:
MFCD00063602
分類程式碼代碼:
12352116
PubChem物質ID:
24278187
NACRES:
NA.77

生物源

synthetic (organic)

化驗

≥97% (TLC)

形狀

powder

mp

162-169 °C (lit.)

溶解度

ethanol: 50 mg/mL, clear to slightly hazy

儲存溫度

2-8°C

SMILES 字串

Cl.N[C@@H]1C[C@H]1c2ccccc2

InChI

1S/C9H11N.ClH/c10-9-6-8(9)7-4-2-1-3-5-7;/h1-5,8-9H,6,10H2;1H/t8-,9+;/m0./s1

InChI 密鑰

ZPEFMSTTZXJOTM-OULXEKPRSA-N

基因資訊

human ... MAOA(4128) , MAOB(4129)

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生化／生理作用

非选择性 MAO-A/B 抑制剂。

特點和優勢

该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面， 请单击此处。
这种化合物是 ADME 毒性研究的特色产品。点击此处发现更多特色 ADME 毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

分析证书(COA)

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Navneet Goyal et al.
Chemical research in toxicology, 36(12), 1973-1979 (2023-11-14)
As a potential means for smoking cessation and consequently prevention of smoking-related diseases and mortality, in this study, our goal was to investigate the inhibition of nicotine metabolism by P450 2A6. Smoking is the main cause of many diseases and
Erin A Clark et al.
Cell reports, 27(12), 3522-3532 (2019-06-20)
KDM1A-mediated H3K4 demethylation is a well-established mechanism underlying transcriptional gene repression, but its role in gene activation is less clear. Here, we report a critical function and mechanism of action of KDM1A in glucocorticoid receptor (GR)-mediated gene transcription. Biochemical purification of
Navneet Goyal et al.
Journal of cancer metastasis and treatment, 7 (2021-11-02)
In this study, our goal was to study the inhibition of nicotine metabolism by P450 2A6, as a means for reduction in tobacco use and consequently the prevention of smoking-related cancers. Nicotine, a phytochemical, is an addictive stimulant, responsible for
Mingxi Weng et al.
Science advances, 9(34), eadh2501-eadh2501 (2023-08-23)
Advanced strategies to interconvert cell types provide promising avenues to model cellular pathologies and to develop therapies for neurological disorders. Yet, methods to directly transdifferentiate somatic cells into multipotent induced neural stem cells (iNSCs) are slow and inefficient, and it
Natallie Kajevu et al.
International journal of molecular sciences, 24(18) (2023-09-28)
We tested a hypothesis that in silico-discovered compounds targeting traumatic brain injury (TBI)-induced transcriptomics dysregulations will mitigate TBI-induced molecular pathology and augment the effect of co-administered antiseizure treatment, thereby alleviating functional impairment. In silico bioinformatic analysis revealed five compounds substantially
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