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Merck
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文件

P6777

Sigma-Aldrich

苯乙肼 硫酸盐

别名:

苯乙肼硫酸氢盐

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About This Item

经验公式（希尔记法）:
C8H12N2 · H2O4S
CAS号:
156-51-4
分子量:
234.27
EC號碼:
205-856-0
MDL號碼:
MFCD00050687
分類程式碼代碼:
12352200
PubChem物質ID:
24278646
NACRES:
NA.77

生物源

synthetic

化驗

≥98% (iodine, titration)

形狀

powder

溶解度

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES 字串

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

InChI 密鑰

RXBKMJIPNDOHFR-UHFFFAOYSA-N

基因資訊

human ... MAOA(4128) , MAOB(4129)

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生化／生理作用

非选择性 MAO-A/B 抑制剂。

特點和優勢

该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面， 请单击此处。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

防範說明

P301 + P310

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Hwan-Suck Chung et al.
Neurochemical research, 37(10), 2117-2124 (2012-07-06)
Phenelzine is a potent monoamine oxidase inhibitor that is used in patients with depression. It is also well known that nitric oxide (NO) synthase inhibitors show preclinical antidepressant-like properties, which suggests that NO is involved in the pathogenesis of depression.
Mee-Sook Song et al.
Journal of neurochemistry, 114(5), 1405-1413 (2010-06-19)
Reactive aldehydes have been implicated in the etiology of several neurological and psychiatric disorders, and there is considerable interest in drugs to counteract the actions of these aldehydes. Increased formaldehyde (FA) and up-regulation of semicarbazide-sensitive amine oxidase, which forms FA
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Nahla Mahgoub et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(2), E24-E25 (2011-06-17)
Darrick T Balu et al.
Brain research, 1211, 37-43 (2008-04-25)
Antidepressant treatments have been proposed to produce their therapeutic effects, in part, through increasing neurotrophin levels in the brain. The current experiments investigated the effects of acute and chronic treatment with different pharmacologic and somatic antidepressant treatments on protein levels
Adeline Su-Yin Ngo et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 431-434 (2010-07-24)
Phenelzine is an irreversible monoamine oxidase inhibitor (MAOI). Hypertensive reactions after ingestion of tyramine-rich foods such as cheese are well known. However, a review of the available medical literature found no previous reports of myocardial infarction resulting from the ingestion
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