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Merck

P0880

Sigma-Aldrich

Pro-Gly

≥98% (TLC), suitable for cell culture

别名:

L-prolyl-glycine

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About This Item

经验公式(希尔记法):
C7H12N2O3
CAS号:
分子量:
172.18
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.26

product name

Pro-Gly,

化驗

≥98% (TLC)

形狀

powder

技術

cell culture | mammalian: suitable

顏色

white

應用

cell analysis

儲存溫度

−20°C

SMILES 字串

OC(=O)CNC(=O)[C@@H]1CCCN1

InChI

1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1

InChI 密鑰

RNKSNIBMTUYWSH-YFKPBYRVSA-N

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生化/生理作用

PRO-GLY is a dipeptide that has previously been shown to prevent progression of diabetes.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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T A Gudasheva et al.
European journal of drug metabolism and pharmacokinetics, 22(3), 245-252 (1997-07-01)
The metabolism of a new piracetam analogue, the dipeptide cognitive enhancer N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111) was studied in vivo. GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection (LOD)
I P Ashmarin et al.
Biochemistry. Biokhimiia, 63(2), 119-124 (1998-06-02)
Our own data and data from the literature on the regulatory role of the simplest proline-containing peptides GP, PG, PGP, GPGG, and cyclic-PG are summarized. These peptides are involved in homeostasis of gastric mucosa and the anticoagulant and fibrinolytic potential
Shigeo Hayakawa et al.
Journal of the American Chemical Society, 129(25), 7936-7949 (2007-06-07)
We report a combined experimental and computational study of the proline effect in model dipeptides Pro-Gly and Gly-Pro. Gas-phase protonated peptide ions were discharged by glancing collisions with potassium or cesium atoms at 3 keV collision energies, and the peptide
Feng-Chun Wu et al.
The Journal of organic chemistry, 74(13), 4812-4818 (2009-05-23)
Tetrapeptides, containing a terminated primary amine and conformationally restricted D-Pro-Gly or D-Pro-Aib (2-aminoisobutanoic acid) segment as a strongly beta-turn-nucleating element, were designed and synthesized with condensation of N-module dipeptides with C-module dipeptides in solution. They were first applied to catalyze
Z Dzakula et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 135(2), 454-465 (1999-01-08)
Analytical expressions have been derived that translate uncertainties in distance constraints (obtained from NMR investigations) into uncertainties in atom positions in the maximum likelihood (ML) structure consistent with these inputs. As a test of this approach, a comparison was made

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