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用途
sufficient for 100 colorimetric tests
應用
cosmetics
food and beverages
檢測方法
colorimetric
相關疾病
neurological disorders; gastrointestinal diseases
儲存溫度
−20°C
一般說明
血流中D-乳酸的浓度通常是纳摩尔级，由肠源或甲基乙二醛途径产生。在哺乳动物中，D-乳酸代谢需要D-乳酸氢化酶且代谢缓慢，因此血液浓度水平增加可导致酸血症和酸中毒。D-乳酸酸中毒的严重程度可能与神经毒性症状有关。体内D-乳酸显著积累也可能与代谢和排泄受损有关。
應用
D-乳酸比色检测试剂盒用于检测产生的乳酸的立体特异性。
適合性
适用于血清、血浆、细胞、培养物和发酵培养基样品。
原則
在该检测中，D-乳酸被D-乳酸氢化酶特异性氧化，产生与之成比例、可在450 nm处进行检测的比色产物。样品中D-乳酸的有效浓度范围是0.1-10 mM。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
William H. Hoffman et al.
Journal of clinical research in pediatric endocrinology, 12(2), 160-167 (2019-09-14)
To determine the time relationships of soluble receptor for glycation end-products (sRAGE), [a decoy of the advanced glycation end-products (AGE)-RAGE axis] and D-lactate, (a metabolite of methylglyoxal) in the inflammatory response to diabetic ketoacidosis (DKA). Sixteen children and adolescents with
Ayca Erkin-Cakmak et al.
The Journal of clinical endocrinology and metabolism, 104(7), 3003-3011 (2019-03-15)
To investigate the link between dietary sugar consumption and two separate pathogenetic mechanisms associated with metabolic syndrome: de novo lipogenesis (DNL) and nonenzymatic glycation. We assessed changes in serum d-lactate (the detoxification end-product of methylglyoxal) concentration in response to 9
Poonam Naik et al.
Current eye research, 45(2), 184-189 (2019-08-31)
Purpose: Microbiological investigations of vitreous fluid have often failed to detect the causative agent in infectious endophthalmitis resulting in a clinical dilemma. D-Lactate is a byproduct of bacterial metabolism, and its accumulation in sterile body fluids indicates bacterial infection. The
Ottavia Benedicenti et al.
Journal of fish diseases, 42(9), 1241-1258 (2019-06-18)
A relationship between increasing water temperature and amoebic gill disease (AGD) prevalence in Atlantic salmon (Salmo salar) has been noted at fish farms in numerous countries. In Scotland (UK), temperatures above 12°C are considered to be an important risk factor
Reyna Rodríguez-Mortera et al.
Clinical chemistry and laboratory medicine, 56(7), 1100-1108 (2018-02-16)
Childhood obesity is associated with insulin resistance (IR), increased levels of small dense low-density lipoprotein (sd-LDL) as well as with augmented hepatic de novo lipogenesis, which implies increased triose phosphate fluxes that may lead to increased methylglyoxal (MG) and its
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