H7666

IL-12 human

HumanKine^®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

• 别名: IL-12
• MDL號碼: MFCD00212975
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• product name: Interleukin-12 human, HumanKine^®, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin, tested
• 生物源: human
• 品質等級: 200
• 重組細胞: expressed in HEK 293 cells
• 化驗: ≥95% (SDS-PAGE)
• 形狀: lyophilized
• 效力: ≤2 ng/mL EC₅₀
• 分子量: dimer 57 kDa (glycosylated)
• 包裝: pkg of 10 μg
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested
• 儲存溫度: −20°C

说明

應用

Interleukin-12 (IL-12) human has been used to study IL-12 mediated enhancement of IL-12Rβ2 (IL-12 receptor) expression.

生化／生理作用

Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.

外觀

lyophilized from a 0.2 μm filtered solution of PBS

分析報告

The specific activity was determined by the dose-dependent release of IFN-γ from the human NK92 cell line in presence of 20 ng/mL rIL-2.

法律資訊

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable