推荐产品
product name
20-羟基-（5Z,8Z,11Z,14Z）-二十碳四烯酸, ~100 μg/mL in ethanol, ≥90% (HPLC)
化驗
≥90% (HPLC)
形狀
liquid
濃度
~100 μg/mL in ethanol
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
InChI
1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
InChI 密鑰
NNDIXBJHNLFJJP-DTLRTWKJSA-N
生化／生理作用
20-羟基-（5Z，8Z，11Z，14Z）-二十碳四烯酸（20-HETE）是通过细胞色素P4504A的花生四烯酸代谢产物，它是Ras/MAP（微管相关蛋白）途径的激活剂。20-HETE酸是肾脏中主要的花生四烯酸。 它参与调节肾小管的钠、钾和氯化物转运。20-HETE通常以葡糖醛酸结合物的形式排泄在尿液中，有时以游离酸的形式排泄。在大鼠妊娠期间观察到尿液20-HETE增加。
包裝
在氩气下包装。
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
57.2 °F - closed cup
閃點（°C）
14.0 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Elevated 12-and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases
Nithipatikom K, et al.
Cancer Letters, 233(2), 219-225 (2006)
Tiago J Costa et al.
Frontiers in physiology, 9, 490-490 (2018-06-06)
Postmenopausal period has been associated to different symptoms such as hot flashes, vulvovaginal atrophy, hypoactive sexual desire disorder (HSDD) and others. Clinical studies have described postmenopausal women presenting HSDD can benefit from the association of testosterone to conventional hormonal therapy.
Anne Barden et al.
Free radical biology & medicine, 42(11), 1730-1735 (2007-04-28)
There is considerable evidence that chronic moderate-to-high alcohol consumption increases blood pressure. The mechanisms by which this occurs are not clear. Alcohol consumption can induce oxidative stress and cytochrome P450 (CYP450) isoforms that are associated with oxidative stress and may
Jonas C Fordsmann et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(6), 2562-2570 (2013-02-09)
Cortical spreading depression (CSD) is associated with release of arachidonic acid, impaired neurovascular coupling, and reduced cerebral blood flow (CBF), caused by cortical vasoconstriction. We tested the hypothesis that the released arachidonic acid is metabolized by the cytochrome P450 enzyme
Lingling Lu et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 39(3), 481-496 (2017-10-27)
Astrocytes express neurotransmitter receptors that serve as sensors of synaptic activity and initiate signals leading to activity-dependent local vasodilation and increases in blood flow. We previously showed that arteriolar vasodilation produced by activation of cortical astrocytes is dependent on endothelial
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门