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product name
菲律宾菌素复合体 来源于菲律宾链霉菌, ≥70% (UV)
生物源
Streptomyces sp. (Streptomyces filipinensis)
品質等級
化驗
≥70% (UV)
形狀
powder
溶解度
methanol: 9.80-10.20 mg/mL, clear to hazy, yellow to very deep greenish-yellow
抗生素活性譜
fungi
作用方式
cell membrane | interferes
儲存溫度
−20°C
InChI
1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1
InChI 密鑰
IMQSIXYSKPIGPD-YQRUMEKGSA-N
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一般說明
化学结构：大环内酯
應用
来自非律平链霉菌的非律平复合物已用作检测细胞中游离胆固醇的荧光探针。
生化／生理作用
菲律平是一种多烯大环内酯类抗生素和抗真菌药。抗真菌作用的机理尚不清楚，但可能是由于膜通透性改变所致。 非律平以形成膜孔的方向与含胆固醇的模型结晶相脂质双层结合，并与具有或没有胆固醇的液相双层结合。它既抑制蛋白（PrP）的内吞作用，又导致 PrP 从质膜释放。
其他說明
非律平包含 8 个异构体成分，其中非律平 III 是主要成分。
相關產品
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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