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Merck

D8015

Sigma-Aldrich

4-二甲氨基安替比林

reactive nitrogen species scavenger

别名:

4-二甲氨基-2,3-二甲基-1-苯基-3-吡唑啉-5-酮, 氨基比林

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About This Item

经验公式(希尔记法):
C13H17N3O
CAS号:
分子量:
231.29
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.77

形狀

solid

mp

107-109 °C (lit.)

SMILES 字串

CN(C)C1=C(C)N(C)N(c2ccccc2)C1=O

InChI

1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3

InChI 密鑰

RMMXTBMQSGEXHJ-UHFFFAOYSA-N

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應用

Fe(VI)的氧化有可能从饮用水中除去N-亚硝基二甲胺前体,包括4-二甲基氨基安替比林。4-二甲氨基安替比林本身是活性氮化合物一氧化氮和过氧亚硝酸盐的有效清除剂,在炎症反应中具有重要作用。

生化/生理作用

当针对鼠伤寒沙门氏菌( Salmonella typhimurium )测试菌株TA100、TA98、TA97、TA102和TA104进行筛选时,发现安替比林无诱变性。

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Alba Rocco et al.
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Although numerous non-invasive tests are currently available to explore liver function and disease activity in patients with HCV-related chronic diseases, none of these indicate the likelihood of disease progression in the individual patient. We aimed at assessing the prognostic ability
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 127, 72-84 (2018-02-11)
The Blood-Brain Barrier (BBB) plays an essential role in protecting the brain tissues against possible injurious substances. In the present work, 79 neutral, basic, acidic and amphoteric structurally unrelated analytes were considered and their chromatographic retention coefficients on immobilized artificial
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Chemerin is a novel protein linked to adipocyte differentiation and the development of metabolic imbalances. We sought to examine the relationship of chemerin with metabolic syndrome disturbances including body fat percentage, serum lipid, glucose, insulin levels and body fat percentage
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Biochemistry, 50(12), 2123-2134 (2011-03-08)
To understand the molecular basis of sequential N-dealkylation by cytochrome P450 2B enzymes, we studied the binding of amidopyrine (AP) as well as the metabolites of this reaction, desmethylamidopyrine (DMAP) and aminoantipyrine (AAP), using the X-ray crystal structure of rabbit
Dipak Samanta et al.
Chemical communications (Cambridge, England), 48(17), 2298-2300 (2012-01-24)
Three-component self-assembly of a cis-blocked 90° Pd(II) acceptor with a mixture of a tetraimidazole and a linear dipyridyl donor self-discriminated into unusual Pd(8) molecular swing (1) and Pd(6) molecular boat (2), which are characterized by single-crystal X-ray diffraction analysis; their

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