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Merck

D6571

Sigma-Aldrich

3′,4′-二甲氧基黄酮

别名:

2-(3,4-二甲氧基苯基)苯并吡喃-4-酮, 3′,4′-DMF

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About This Item

经验公式(希尔记法):
C17H14O4
CAS号:
分子量:
282.29
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to off-white

溶解度

DMSO: ≥20 mg/mL

儲存溫度

room temp

SMILES 字串

COc1ccc(cc1OC)C2=CC(=O)c3ccccc3O2

InChI

1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3

InChI 密鑰

ZGHORMOOTZTQFL-UHFFFAOYSA-N

應用

3′,4′-二甲氧基黄酮已被用于脲酶抑制试验。

生化/生理作用

3′,4′-二甲氧基黄酮是AhR的竞争性拮抗剂,其可抑制AhR介导的CYP1A1诱导,并且还在乳腺肿瘤细胞系中显示出抗雌激素活性。该化合物可阻断细胞溶质AhR复合物的转化,并形成核AhR复合物。
3′,4′-二甲氧基黄酮是一种黄酮化合物,其具有防止聚(ADP-核糖)(PAR)聚合物的产生和积累的能力。它可在皮质神经元中防御 N-甲基-D-天冬氨酸(NMDA)的毒性。3′,4′-二甲氧基黄酮是植物来源的多酚类黄酮类的成员。已知它具有抗氧化、抗癌、抗炎、抗动脉粥样硬化、降血脂和神经保护或神经营养作用。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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