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化驗
≥98% (HPLC)
形狀
powder
顏色
white to off-white
溶解度
DMSO: ≥20 mg/mL
儲存溫度
room temp
SMILES 字串
COc1ccc(cc1OC)C2=CC(=O)c3ccccc3O2
InChI
1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3
InChI 密鑰
ZGHORMOOTZTQFL-UHFFFAOYSA-N
應用
3′,4′-二甲氧基黄酮已被用于脲酶抑制试验。
生化/生理作用
3′,4′-二甲氧基黄酮是AhR的竞争性拮抗剂,其可抑制AhR介导的CYP1A1诱导,并且还在乳腺肿瘤细胞系中显示出抗雌激素活性。该化合物可阻断细胞溶质AhR复合物的转化,并形成核AhR复合物。
3′,4′-二甲氧基黄酮是一种黄酮化合物,其具有防止聚(ADP-核糖)(PAR)聚合物的产生和积累的能力。它可在皮质神经元中防御 N-甲基-D-天冬氨酸(NMDA)的毒性。3′,4′-二甲氧基黄酮是植物来源的多酚类黄酮类的成员。已知它具有抗氧化、抗癌、抗炎、抗动脉粥样硬化、降血脂和神经保护或神经营养作用。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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