价格与库存信息目前不能提供
推荐产品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
CY-A1, monoclonal
分子量
antigen 60 kDa
包含
15 mM sodium azide
物種活性
mouse, human, monkey, bovine
技術
immunocytochemistry: suitable
microarray: suitable
western blot: 1:1,000 using a mouse NIH 3T3 cell extract
同型
IgG2a
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CCNA2(890)
mouse ... Ccna2(12428)
一般說明
细胞周期蛋白 A 是 S 期的核蛋白，它与 cdk2 和 cdc2 结合。与细胞周期蛋白 A 特异性反应的单克隆抗体的可用性使得细胞周期蛋白 A 的亚细胞检测和定位，以及细胞周期蛋白水平的相对差异（作为细胞周期阶段的功能）的测量成为可能。
特異性
该抗体识别牛细胞周期蛋白 A 氨基酸 162-433 中存在的表位。未发现与其他细胞周期蛋白（细胞周期蛋白 B、D 或 E）有交叉反应。
免疫原
重组牛细胞周期蛋白 A。
應用
小鼠单克隆抗 Cyclin A 抗体适用于：
- 免疫细胞化学
- 微阵列
- 蛋白质印迹（使用小鼠 NIH 3T3 细胞提取物，1：1,000 稀释）
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Qing-Hua Zhang et al.
The Journal of cell biology, 216(10), 3133-3143 (2017-08-19)
Cyclin A2 is a crucial mitotic Cdk regulatory partner that coordinates entry into mitosis and is then destroyed in prometaphase within minutes of nuclear envelope breakdown. The role of cyclin A2 in female meiosis and its dynamics during the transition
Emma L Hesketh et al.
Cell cycle (Georgetown, Tex.), 14(3), 333-341 (2015-02-07)
The minichromosome maintenance complex (MCM2-7) is the putative DNA helicase in eukaryotes, and essential for DNA replication. By applying serial extractions to mammalian cells synchronized by release from quiescence, we reveal dynamic changes to the sub-nuclear compartmentalization of MCM2 as
J E Dazard et al.
Oncogene, 19(33), 3693-3705 (2000-08-19)
p53 transcription factor is mutated in most skin cell carcinomas and in more than 50% of all human malignancies. One of its transcriptional targets is MDM2, which in turn down-regulates p53. The role of the p53/MDM2 regulatory loop upon genotoxic
Matthew Hoare et al.
Nature cell biology, 18(9), 979-992 (2016-08-16)
Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse secretome, which provides complex functionality for senescent cells within the tissue microenvironment. We show that oncogene-induced senescence is accompanied by a dynamic fluctuation of NOTCH1 activity, which
T-Y Chen et al.
Oncogenesis, 4, e180-e180 (2015-12-23)
The antitumor drug etoposide (ETO) is widely used in treating several cancers, including adrenocortical tumor (ACT). However, when used at sublethal doses, tumor cells still survive and are more susceptible to the recurring tumor due to centrosome amplification. Here, we
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