推荐产品
生物源
synthetic (organic)
化驗
≥98% (TLC)
形狀
powder
mp
>270 °C
溶解度
H2O: 100 mg/mL
DMSO: soluble (lit.)(lit.)
methanol: soluble (lit.)(lit.)
儲存溫度
2-8°C
SMILES 字串
[K+].CC1(C)N([O])C(c2ccc(cc2)C([O-])=O)=[N+]([O-])C1(C)C
InChI
1S/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q;+1/p-1
InChI 密鑰
VYEUQMVIGXFZQU-UHFFFAOYSA-M
正在寻找类似产品? 访问 产品对比指南
一般說明
2-(4-羧苯基)-4,4,5,5-四甲基咪唑啉-1-氧基-3-氧化物(羧基-PTIO)主要被认为是一氧化氮(NO)清除剂。
應用
羧基-PTIO钾盐通过检查反应混合物中羟基自由基或硝酸的生成情况,确定反应混合物中一氧化氮的生成情况。还可添加至神经元,分析其对葡萄糖/氧气/血清剥夺(GOSD)状态的影响(4)
生化/生理作用
其与一氧化氮反应可形成羧基-PTI衍生物,产物可进一步抑制一氧化氮合成酶的活性。
羧基-PTIO可以与一氧化氮(NO)快速反应生成二氧化氮(NO2)。 可用于预防 体内脂多糖刺激引起的低血压和内毒素性休克。羧基-PTIO还可以阻断 体外 NO刺激造成的血管松弛。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Molecules (Basel, Switzerland), 24(6) (2019-03-27)
Doxycycline (DOXY) is an antibiotic routinely prescribed in human and veterinary medicine for antibacterial treatment, but it has also numerous side effects that include oxidative stress, inflammation, cancer or hypoxia-induced injury. Endogenously produced hydrogen sulfide (H₂S) and polysulfides affect similar
International journal of molecular sciences, 20(18) (2019-09-07)
Previously, we investigated the dose response for chromosomal aberration (CA) for exposures corresponding to less than one particle traversal per cell nucleus by high energy and charge (HZE) particles, and showed that the dose responses for simple exchanges for human
Nitric oxide scavenger carboxy-PTIO potentiates the inhibition of dopamine uptake by nitric oxide donors
European Journal of Pharmacology, 448(1), 27-30 (2002)
Nitric oxide : biology and chemistry, 65, 43-49 (2017-02-27)
Bacterial biofilms show high tolerance towards antibiotics and are a significant problem in clinical settings where they are a primary cause of chronic infections. Novel therapeutic strategies are needed to improve anti-biofilm efficacy and support reduction in antibiotic use. Treatment
Interference of carboxy-PTIO with nitric oxide-and peroxynitrite-mediated reactions
Free Radical Biology & Medicine, 22(5), 787-794 (1997)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门