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Merck

A7736

Sigma-Aldrich

白蛋白 人

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

别名:

Albagen, rHSA

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About This Item

经验公式(希尔记法):
C2936H4624N786O889S41
CAS号:
分子量:
66471.53
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25

生物源

human

重組細胞

expressed in Pichia pastoris

化驗

≥90% (agarose gel electrophoresis)

形狀

lyophilized powder

分子量

monomer ~67 kDa

技術

cell culture | mammalian: suitable

UniProt登錄號

儲存溫度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI 密鑰

QYSGYZVSCZSLHT-UHFFFAOYSA-N

基因資訊

human ... ALB(213)

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應用

该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

生化/生理作用

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

物理性質

从N端删除单个Asp可产生低过敏性构建体。X射线晶体学证实了其与天然白蛋白的结构等同性。Asp缺失通过消除白蛋白主要的铜镍结合位点而去除了重要的抗原决定簇。人白蛋白的前三个残基被认为是非结构性的。还在Cys34上进行阻断,以改善稳定性、单体含量和均一性。

其他說明

更多信息参见人血清白蛋白

法律資訊

Albagen is a trademark of Albumin Therapeutics, LLC.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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The receptor for advanced glycation end-products (RAGE) recognizes several ligands involved in inflammatory diseases. Two circulating soluble isoforms exist: esRAGE derived from alternative splicing and cRAGE generated by the membrane-bound RAGE (FL-RAGE) proteolysis. Together, esRAGE and cRAGE constitute sRAGE and
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