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Merck

91211

Sigma-Aldrich

氧化白藜芦醇

≥97.0% (HPLC)

别名:

(E)-2,3′,4,5′-二苯乙烯四醇, 2,3′,4,5′-四羟基-反式-二苯乙烯, 4-[(1E)-2-(3,5-二羟苯基) -乙烯基]-1,3-苯二酚

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About This Item

经验公式(希尔记法):
C14H12O4
CAS号:
分子量:
244.24
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25

化驗

≥97.0% (HPLC)

形狀

solid

應用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES 字串

Oc1ccc(\C=C\c2cc(O)cc(O)c2)c(O)c1

InChI

1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+

InChI 密鑰

PDHAOJSHSJQANO-OWOJBTEDSA-N

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一般說明

氧化白藜芦醇(OXY或ORV)是一种天然存在的多酚二苯乙烯,主要存在于许多植物的心材中。它主要是从 野波罗蜜 中提取,, 也是这种植物的主要成分之一。ORV 具有非常简单的化学结构,其核心是反式-1,2-二苯基乙烯,每个芳环上都有两个羟基 (OH)。

應用

氧化白藜芦醇已被用于:
  • 与聚乳酸-乙醇酸共聚物(PLGA) 纳米颗粒一起用于测试其抗氧化作用并研究其在抑制超氧阴离子(O2-) 生成中的作用
  • 测试其作为抗神经炎症剂对白细胞介素 1 β (IL-1β)诱导的 HMC3 人小胶质细胞系的影响
  • 作为参考标准品用于确定其是否存在于野波罗蜜中。使用高效液相色谱法 (HPLC)提取的(AL)提取物

生化/生理作用

氧化白藜芦醇因其多样的生物学和药理学特性而广为人知。氧化白藜芦醇是一种强效抗氧化剂和抗炎剂。ORV 还具有神经保护作用,可防止脑缺血、中风和多种神经退行性疾病。它还显示出抗癌、抗菌、保肝的特性,并防止其它多种代谢疾病。它还是一种强效酪氨酸酶抑制剂。

包裝

无底玻璃瓶。内容物在插入式融锥内。

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jin Hee Choi et al.
International journal of molecular sciences, 20(1) (2018-12-24)
The phytochemical oxyresveratrol has been shown to exert diverse biological activities including prevention of obesity. However, the exact reason underlying the anti-obese effects of oxyresveratrol is not fully understood. Here, we investigated the effects and mechanism of oxyresveratrol in adipocytes
Shaida A Andrabi et al.
Brain research, 1017(1-2), 98-107 (2004-07-21)
Oxidative stress is one of the major pathological factors in the cascade that leads to cell death in cerebral ischemia. Here, we investigated the neuroprotective effect of a naturally occurring antioxidant, oxyresveratrol, to reduce brain injury after cerebral stroke. We
Kittisak Likhitwitayawuid
Molecules (Basel, Switzerland), 26(14) (2021-07-25)
Oxyresveratrol has recently attracted much research attention due to its simple chemical structure and diverse therapeutic potentials. Previous reviews describe the chemistry and biological activities of this phytoalexin, but additional coverage and greater accessibility are still needed. The current review
Yi-Ching Chen et al.
BMC complementary and alternative medicine, 13, 45-45 (2013-02-26)
Morus alba has long been used in traditional Chinese medicine to treat inflammatory diseases; however, the scientific basis for such usage and the mechanism of action are not well understood. This study investigated the action of M. alba on leukocyte
John T Weber et al.
European journal of pharmacology, 680(1-3), 55-62 (2012-04-11)
Oxyresveratrol is a potent antioxidant and free-radical scavenger found in mulberry wood (Morus alba L.) with demonstrated protective effects against cerebral ischemia. We analyzed the neuroprotective ability of oxyresveratrol using an in vitro model of stretch-induced trauma in co-cultures of

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