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Merck

S0100000

沙丁胺醇

European Pharmacopoeia (EP) Reference Standard

别名:

α-[(-丁基氨基)甲基]-4-羟基--二甲苯-α,α′-二醇, Albuterol

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About This Item

经验公式(希尔记法):
C13H21NO3
CAS号:
分子量:
239.31
Beilstein:
6405698
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

albuterol, salbutamol

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)NCC(O)c1ccc(O)c(CO)c1

InChI

1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

InChI 密鑰

NDAUXUAQIAJITI-UHFFFAOYSA-N

基因資訊

human ... ADRB2(154)

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

應用

沙丁胺醇EP 参考标准品设计用于欧洲药典规定的实验室测试。

生化/生理作用

β2-肾上腺素受体激动剂

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制。

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价格

象形圖

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訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2


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Karim Makhlouf et al.
CNS drugs, 16(1), 1-8 (2002-01-05)
The beta2-adrenergic receptor agonist salbutamol (albuterol) has been used for many years in the treatment of bronchospasm in patients with asthma. In this patient group, salbutamol is a relatively safe and inexpensive drug, and is easy to administer. Within the
Jean-Louis Pepin et al.
Chest, 146(6), 1521-1530 (2014-07-25)
Increased arterial stiffness as measured by aortic pulse wave velocity (aPWV) predicts cardiovascular events and mortality and is elevated in patients with COPD. Prior investigation suggests that a long-acting β-agonist (LABA)/inhaled corticosteroid (ICS) lowers aPWV in patients with baseline aPWV
Thomas Ritz et al.
Chest, 146(5), 1237-1247 (2014-08-15)
Hyperventilation has been associated with adverse effects on lung function, symptoms, and well-being in asthma. We examined whether raising end-tidal CO2 levels (ie, Pco2) compared with slow breathing is associated with improvements in asthma control, including peak flow variability. One
L Gnatiuc et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 19(1), 21-30 (2014-12-19)
Increasing access to essential respiratory medicines and influenza vaccination has been a priority for over three decades. Their use remains low in low- and middle-income countries (LMICs), where little is known about factors influencing use, or about the use of
S E Libretto
Archives of toxicology, 68(4), 213-216 (1994-01-01)
This paper reviews the published toxicology of salbutamol. Salbutamol is a relatively selective beta 2-adrenoreceptor stimulant with rapid, potent bronchodilator activity and only minor inotropic or chronotropic effects. It was not found to be mutagenic. LD50 values and other acute

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