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RSHMAG-69K

Millipore

MILLIPLEX® 大鼠应激激素磁珠面板-内分泌多重检测

This MILLIPLEX MAP Rat Stress Hormone Magnetic Bead Panel is an Endocrine multiplex assay. The analytes available for this multiplex kit are: ACTH, Corticosterone, Melatonin.

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質等級

物種活性

rat

製造商/商標名

Milliplex®

assay range

accuracy: 61%
(Corticosterone)

accuracy: 83%
(ACTH)

sensitivity: 0.9 pg/mL
(ACTH)

sensitivity: 1.52 pg/mL
(Melatonin)

sensitivity: 2914 pg/mL
(Corticosterone)

standard curve range: 0.55-400 pg/mL
(Melatonin)

standard curve range: 1.4-1,000 pg/mL
(ACTH)

standard curve range: 686-500,000 pg/mL
(Corticosterone)

inter-assay cv: <15%
intra-assay cv: <10%

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

一般說明

应激被定义为通过生理和/或心理刺激或应激源破坏体内稳态。在生理上,包括下丘脑、垂体和肾上腺在内的神经内分泌系统在应激反应中起关键作用。在促肾上腺皮质激素释放激素(CRH)和精氨酸加压素(AV)的激活下,垂体释放ACTH,导致肾上腺分泌皮质醇/皮质酮和其他糖皮质激素。这些皮质激素在应激反应中涉及全身,并通过对下丘脑的负反馈回路参与应激反应的终止。皮质酮和褪黑激素在调节睡眠-觉醒周期中很重要。

MILLIPLEX® 大鼠应激激素面板是一种3重试剂盒,用于同时定量血清、血浆、组织/细胞提取物或培养基样品中的以下任何或所有分析物:ACTH,皮质酮和/或褪黑激素。该试剂盒采用96孔板,包含冻干标准混合物、两个内部检测质控品,最多可测量38份样本,一式两份。

Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省有价值的样品量。

面板类型:内分泌

特異性

交叉反应性
此检测试剂在检测板内显示不显著的交叉反应性

應用

  • 分析物:ACTH、皮质酮、褪黑激素
  • 推荐样品类型:大鼠血清、血浆、细胞/组织上清液和裂解物
  • 注:为了获得浑浊的血清和血浆样品的最佳分析性能,提供了提取方案。
  • 建议的样品稀释度:每孔25 μL用于以下方面:未稀释的提取血清或血浆;1:4未提取的血清或血浆;细胞/组织培养样品可能需要在适当的对照培养基中稀释。
  • 分析运行时间:在2-8℃下过夜(16-18小时)
  • 研究类别:内分泌
  • 研究子类别:代谢

特點和優勢

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他說明

请联系技术服务部了解稀释线性。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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Brooks A Gross et al.
Journal of neuroscience methods, 251, 83-91 (2015-05-28)
Sleep deprivation via gentle handling is time-consuming and personnel-intensive. We present here an automated sleep deprivation system via air puffs. Implanted EMG and EEG electrodes were used to assess sleep/waking states in six male Sprague-Dawley rats. Blood samples were collected
Vitor Silva Pereira et al.
Acta neuropsychiatrica, 31(5), 258-265 (2019-06-25)
Treatment-resistance to antidepressants is a major problem in the pharmacotherapy of major depressive disorder (MDD). Unfortunately, only a few animal models are suitable for studying treatment-resistant depression, among them repeated treatment with Adrenocorticotropic hormone (ACTH) appears to be useful to
Viviane S Hambrecht-Wiedbusch et al.
Sleep, 40(9) (2017-09-22)
Sleep and pain are reciprocally related, but the precise mechanisms underlying this relationship are poorly understood. This study used a rat model of surgical pain to examine the effect of previous sleep loss on postoperative pain and tested the hypothesis
Chris P Jew et al.
PloS one, 8(8), e70415-e70415 (2013-08-14)
The group I metabotropic glutamate receptor 5 (mGluR5) has been implicated in the pathology of various neurological disorders including schizophrenia, ADHD, and autism. mGluR5-dependent synaptic plasticity has been described at a variety of neural connections and its signaling has been
Milene L Brownlow et al.
Frontiers in molecular neuroscience, 10, 129-129 (2017-05-31)
Nutritional ketosis may enhance cerebral energy metabolism and has received increased interest as a way to improve or preserve performance and resilience. Most studies to date have focused on metabolic or neurological disorders while anecdotal evidence suggests that ketosis may

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了解在实验室、伴生和农业动物研究中使用生物标志物多重免疫检测产品的优势,探索MILLIPLEX®多重检测试剂盒在兽医学和动物健康研究方面的应用。

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