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Key Documents

8.52036

Sigma-Aldrich

Fmoc-Hyp(tBu)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem®

别名:

Fmoc-Hyp(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-trans-4-hydroxyproline

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About This Item

经验公式(希尔记法):
C24H27NO5
分子量:
409.47
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.22

product name

Fmoc-Hyp(tBu)-OH, Novabiochem®

品質等級

產品線

Novabiochem®

化驗

≥95.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

mp

63 °C

應用

peptide synthesis

官能基

hydroxyl

儲存溫度

15-25°C

InChI

1S/C24H27NO5/c1-24(2,3)30-15-12-21(22(26)27)25(13-15)23(28)29-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,27)/t15-,21+/m1/s1

InChI 密鑰

WPBXBYOKQUEIDW-VFNWGFHPSA-N

一般說明

Standard building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

應用

  • Rational design of plant hairpin-like peptide EcAMP1: Structural–functional correlations to reveal antibacterial and antifungal activity: Discusses the use of Fmoc-Hyp(tBu)-OH in designing peptides that exhibit significant antibacterial and antifungal properties (Barashkova et al., 2022).

聯結

Replaces: 04-12-1078

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.50 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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