跳转至内容
Merck
所有图片(1)

Key Documents

516705

Sigma-Aldrich

o-Phenanthroline

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.

别名:

o-Phenanthroline, 1,10-Phenanthroline Monohydrate

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C12H8N2 · xH2O
CAS号:
分子量:
180.21 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.77

品質等級

化驗

≥99% (titration)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

顏色

white to cream

溶解度

DMSO: 100 mg/mL
ethanol: 25 mg/mL
water: 3 mg/mL

運輸包裝

ambient

儲存溫度

10-30°C

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI 密鑰

PPQJCISYYXZCAE-UHFFFAOYSA-N

一般說明

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a general matrix metalloproteinase inhibitor. Forms a red chelate with Fe2+ that absorbs maximally at 510 nm. Can be used as a photometric reagent for iron.
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a metalloprotease inhibitor. Inhibits glioma invasion in vitro.

生化/生理作用

Cell permeable: no
Primary Target
Metalloprotease inhibitor
Product does not compete with ATP.
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Toxic (F)

其他說明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Stix, B., et al. 2001. Am. J. Pathol.159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res.447, 221.
Wang, Y., et al. 1999. J. Biol. Chem.274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Joka Pipercevic et al.
Nature communications, 14(1), 2645-2645 (2023-05-09)
Many proteins involved in eukaryotic phosphate homeostasis are regulated by SPX domains. In yeast, the vacuolar transporter chaperone (VTC) complex contains two such domains, but mechanistic details of its regulation are not well understood. Here, we show at the atomic
Nuria Gutierrez-Prat et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(29) (2021-07-18)
Cell survival in response to stress is determined by the coordination of various signaling pathways. The kinase p38α is activated by many stresses, but the intensity and duration of the signal depends on the stimuli. How different p38α-activation dynamics may
Paul Y Bi et al.
Communications biology, 7(1), 391-391 (2024-03-31)
Mitochondrial stress inducers such as carbonyl cyanide m-chlorophenyl hydrazone (CCCP) and oligomycin trigger the DELE1-HRI branch of the integrated stress response (ISR) pathway. Previous studies performed using epitope-tagged DELE1 showed that these stresses induced the cleavage of DELE1 to DELE1-S

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门