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Merck
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165304

Sigma-Aldrich

D-(–)-2-氨基-5-膦酰戊酸

≥97% (HPLC), solid, NMDA receptor antagonist, Calbiochem®

别名:

D-(–)-2-氨基-5-膦酰戊酸, D-AP5,NMDA拮抗剂II,APV,D-APV,2-APV,D-2-氨基-5-磷酸戊酸

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About This Item

经验公式(希尔记法):
C5H12NO5P
CAS号:
分子量:
197.13
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NA.77

product name

D-(–)-2-氨基-5-膦酰戊酸, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

品質等級

化驗

≥97% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated (hygroscopic)
protect from light

顏色

white

溶解度

dilute aqueous base: 1 mg/mL
water: 1 mg/mL

運輸包裝

ambient

儲存溫度

2-8°C

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1

InChI 密鑰

VOROEQBFPPIACJ-SCSAIBSYSA-L

一般說明

一种DL-2-氨基-5-膦基戊酸(AP5)的活性对映体,是一种常用的竞争性NMDA受体拮抗剂。
一种DL-2-氨基-5-膦基戊酸(AP5)的活性对映体,通常用作竞争性NMDA受体拮抗剂。还抑制辣椒素诱导的脊髓物质P的释放。

生化/生理作用

主要靶标
NMDA受体拮抗剂
产物不与ATP竞争。
可逆:否
细胞渗透性:否

警告

毒性:刺激性(B)

重構

复溶后,等分并冷冻保存(-20°C)。储备液在-20°C条件下可稳定保存6个月。

其他說明

Malcangio, M., et al. 1998.Br. J. Pharmacol.125, 1625.
Schulte, M.K., et al. 1994.Brain Res. 649, 203.
Davis, S., et al. 1992.J. Neurosci. 12, 21.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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