1.00681

琥珀酸

crystalline, EMPROVE^® ESSENTIAL, ChP, NF, JPE, ACS

• 别名: 丁二酸
• 线性分子式: HOOCCH₂CH₂COOH
• CAS号: 110-15-6
• 分子量: 118.09
• Beilstein: 1754069
• MDL號碼: MFCD00002789
• 分類程式碼代碼: 12352106
• 酶委員會索引編號: 203-740-4

属性

• 等級: ACS reagent
• 品質等級: 500
• agency: ChP; JPE; NF
• 產品線: EMPROVE^® ESSENTIAL
• 化驗: 99.0-100.5% (HPLC)
• 形狀: crystalline; solid
• 自燃溫度: 470 °C
• 技術: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• bp: 235 °C (lit.); 235 °C/1013 hPa
• mp: 184-186 °C (lit.)
• 轉變溫度: flash point 206 °C
• 溶解度: 58 g/L
• 密度: 1.56 g/cm³ at 20 °C
• 負離子痕跡: chloride (Cl^-): ≤0.001%; phosphate (PO₄^3-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• 正離子痕跡: As: ≤0.0002%; Fe: ≤5 ppm; heavy metals (as Pb): ≤0.0020%; heavy metals (as Pb): ≤5 ppm
• 應用: liquid formulation; pharma/biopharma processes; pharmaceutical; solid formulation
• 儲存溫度: 2-30°C
• SMILES 字串: OC(=O)CCC(O)=O
• InChI: 1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
• InChI 密鑰: KDYFGRWQOYBRFD-UHFFFAOYSA-N

说明

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Succinic acid is a commonly used ingredient in pharmaceutical applications. In such applications it has been used primarily for solid oral dosage forms.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H318
• 防範說明: P280 - P305 + P351 + P338
• 危險分類: Eye Dam. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable