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等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
cannabis testing
cannabis testing
包装形式
single component solution
储存温度
−20°C
SMILES字符串
O1C(C2C(CC(=CC2)C)c3c1cc(cc3O)CCCCC)(C)C
InChI
1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3
InChI key
HCAWPGARWVBULJ-UHFFFAOYSA-N
一般描述
认证溶液标准品适用于大麻素测试、临床毒理学、法医分析或尿液药物测试的LC/MS或GC/MS应用。Δ8-THC是合成THC生产工艺中的杂质。Δ8-THC 是大麻主要精神活性成分（称为 Δ9-四氢大麻酚）的双键异构体。这种大麻素具有止吐、抗焦虑、刺激食欲和镇痛作用。
应用
这种认证的峰值溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 进行 (−)-Δ8-THC 测试，从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。该认证标准物质（CRM）还可作如下用途：
- 根据国际药品注册协调会议（ICH）分析方法验证三方指南，通过 HPLC-UV 方法对不同大麻品种的生物质和提取物中的 11 种大麻素进行多重分析
- 使用等度高效液相色谱（HPLC）结合二极管阵列检测器（DAD）分离和估算不同大麻产品中的 13 种大麻素
- 使用气相色谱-质谱（GC-MS）分析硅烷化和酯化衍生后从大麻花序中提取的 10 种主要大麻素
- 使用超高效液相色谱（UHPLC）结合三重四极杆质谱法在液-液萃取后定量测定人血浆样品中的大麻二酚和 Δ9-四氢大麻酚，以及鉴定少量大麻素
- 基于 QuEChERS 提取 20 种食品样品中的 15 种大麻素，然后通过液相色谱-串联质谱法（LC-MS/MS）定量
特点和优势
- 完全符合 ISO/IEC 17025 和 ISO 17034 认证
- 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
- 通过实时稳定性研究严格测试，以确保准确性和保质期
- 使用合格的精密天平进行重量准备，以确保最小不确定性
- 氩气环境下火焰密封，装入安瓿以便长期保存
- 提供方便的 DEA 豁免格式，以提高实验室效率
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
51.8 °F - closed cup
闪点(°C)
11.0 °C - closed cup
其他客户在看
A Charalambous et al.
Pharmacology, biochemistry, and behavior, 40(3), 509-512 (1991-11-01)
-(-)-5'-Bromo-delta 8-THC, (-)-5'-trifluoromethyl-delta 8-THC, (-)-5'-iodo-delta 8-THC, (-)-5'-fluoro-delta 8-THC, (-)-11-fluoro-delta 8-THC and (-)-2-iodo-delta 8-THC were synthesized and evaluated in male ICR mice for their effects on sedation, temperature, catalepsy and antinociception following intravenous injection. The analogs were also tested for relative
Spyros P Nikas et al.
The AAPS journal, 6(4), e30-e30 (2005-03-12)
The presence of halogens within the classical cannabinoid structure leads to large variations in the compounds' potencies and affinities for the CB1 receptors. To explore the structure activity relationships within this class of analogs we have used a series of
Nissar A Darmani et al.
European journal of pharmacology, 563(1-3), 187-196 (2007-03-17)
Xenobiotic cannabinoid CB1/CB2-receptor agonists appear to possess broad-spectrum antiemetic activity since they prevent vomiting produced by a variety of emetic stimuli including the chemotherapeutic agent cisplatin, serotonin 5-HT3-receptor agonists, dopamine D2/D3-receptor agonists and morphine, via the stimulation of CB1-receptors. The
A Abrahamov et al.
Life sciences, 56(23-24), 2097-2102 (1995-01-01)
Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9-tetrahydrocannabinol (delta-9-THC), was administered (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up
Christian D Schubart et al.
Schizophrenia research, 130(1-3), 216-221 (2011-05-20)
Cannabis is associated with psychotic outcomes in numerous studies, an effect that is commonly attributed to Δ (9)-tetrahydrocannabinol (Δ 9-THC). An increasing number of authors identify cannabidiol, another component of the cannabis plant, as an antipsychotic agent. The objective of
商品
Cannabis products need cannabinoid characterization. Ascentis Express C18 resolves 14 similar cannabinoids in under seven minutes with excellent peak shape.
Cannabis products need cannabinoid characterization. Ascentis Express C18 resolves 14 similar cannabinoids in under seven minutes with excellent peak shape.
Cannabis products need cannabinoid characterization. Ascentis Express C18 resolves 14 similar cannabinoids in under seven minutes with excellent peak shape.
实验方案
HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.
HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.
HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.
HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.
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