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Merck

M-015

Supelco

安眠酮标准液 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C16H14N2O
CAS号:
分子量:
250.30
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

形狀

liquid

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

濃度

1 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

InChI

1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChI 密鑰

JEYCTXHKTXCGPB-UHFFFAOYSA-N

一般說明

甲喹酮是一种镇静催眠药和中枢神经系统抑制剂,其以商品名Quaalude进行销售,可用于治疗失眠症。甲喹酮也有滥用的历史,其以迪斯科饼干、Lemmons和714s等街头名称闻名。此认证的溶液标准品可作为校准物或对照品中的起始材料,通过LC/MS或GC/MS,用于从尿液药物测试到法医分析和临床毒理学方面的各种应用中。

應用


  • Pharmacokinetic studies: The analysis of Methaqualone in pharmacokinetic research employs liquid chromatography/tandem mass spectrometry, crucial for understanding its metabolism and excretion patterns. Such studies are vital for developing safety profiles and therapeutic guidelines for sedative-hypnotics (Yun et al., 2007).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


分析证书(COA)

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N Fucci
The American journal of forensic medicine and pathology, 17(3), 231-232 (1996-09-01)
A case of acute intoxication of both methaqualone and diphenhydramine is reported. The analysis of these compounds was performed by liquid-liquid extraction (Toxi-Lab DPC procedure) followed by gas chromatography/mass spectrometry determination; both substances are contained in the pharmaceutical formulation called
Guo-Zhou Zhi et al.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 22(4), 335-337 (2002-10-23)
KR-100 is a newly developed long-lasting insecticide that incorporates cinerins substance, drug-release control substance and synergistic agent following certain procedures under carefully regulated conditions. Tests of the efficacy, toxicity, stability and long-term effect of KR-100 were conducted, and it was
G McCarthy et al.
The Cochrane database of systematic reviews, (2)(2), CD004146-CD004146 (2005-04-23)
Methaqualone is a potent quinazoline, a class of sedative-hypnotics, that has a high potential for abuse. While the oral use of methaqualone (Quaalude, Mandrax) has waned in western countries since the mid-late 1980's, the practice of smoking methaqualone is a
Reinhard A Uebel et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 92(7), 547-549 (2002-08-29)
Urine samples that tested positive for two drugs of abuse, namely cannabis and methaqualone, were reassayed in the presence or absence of common household chemicals: Jik (sodium hypochlorite), Dettol (chloroxylenol), G-cide Plus (glutaraldehyde), Perle Hand Soap, ethanol, isopropanol and peroxide
A Ceschi et al.
Clinical toxicology (Philadelphia, Pa.), 51(1), 54-57 (2013-01-10)
Methylmethaqualone is a sedative designer drug created by adding a methyl group to the 3-phenyl ring of methaqualone, and is at present not subject to restrictive regulation in many countries. To our knowledge, no case of methylmethaqualone abuse has been

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