推荐产品
化驗
≥97.0%
折射率
n20/D 1.588 (lit.)
bp
286 °C (lit.)
密度
1.062 g/mL at 25 °C (lit.)
SMILES 字串
C1CN(CCN1)c2ccccc2
InChI
1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2
InChI 密鑰
YZTJYBJCZXZGCT-UHFFFAOYSA-N
基因資訊
mouse ... Htr3a(15561)
rat ... Drd2(24318) , Htr1a(24473)
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訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
284.0 °F
閃點（°C）
140 °C
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
其他客户在看
Gilda Neves et al.
Pharmacology, biochemistry, and behavior, 89(1), 23-30 (2007-12-18)
Previous studies have demonstrated that LASSBio-579 and LASSBio-581, two N-phenylpiperazine derivatives designed for the treatment of schizophrenia, are presynaptic dopamine D(2) receptor agonists that induce a hypothermic effect in mice that is not mediated by dopamine receptor activation. The aim
Romano Di Fabio et al.
Journal of medicinal chemistry, 52(10), 3238-3247 (2009-04-25)
In an effort to discover novel druglike NK(1) receptor antagonists a new series of suitably substituted C-phenylpiperazine derivatives was identified by an appropriate chemical exploration of related N-phenylpiperazine analogues, with the specific aim to maximize their in vitro affinity and
Jadwiga Handzlik et al.
Bioorganic & medicinal chemistry, 20(7), 2290-2303 (2012-03-03)
An association between α(1)-adrenoceptor affinities, hERG K(+)-antagonistic properties and antiarrhythmic activities for a series of phenylpiperazine derivatives of hydantoin (2a-21a) was investigated. New compounds were synthesized and tested for their affinity for α(1)-adrenoceptors in radioligand binding assay using [(3)H]-prazosin as
Daniela Huber et al.
Bioorganic & medicinal chemistry, 20(1), 455-466 (2011-11-22)
Merging two arylamidoalkyl substituted phenylpiperazines as prototypical recognition elements for dopamine D(2)-like receptors by oligoethylene glycol linkers led to a series of bivalent ligands. These dimers were investigated in comparison to their monomeric analogues for their dopamine D(2long), D(2short), D(3)
Rodolfo do Couto Maia et al.
Expert opinion on therapeutic patents, 22(10), 1169-1178 (2012-09-11)
The N-phenylpiperazine subunit represents one of the most versatile scaffolds used in the medicinal chemistry field. Recently, some N-phenylpiperazine derivatives have reached late stage clinical trials for the treatment of CNS disorders, thus, this is clearly a molecular template that
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