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Merck

C117307

Sigma-Aldrich

溴代环丙烷

99%

别名:

环丙基溴

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About This Item

经验公式(希尔记法):
C3H5Br
CAS号:
分子量:
120.98
Beilstein:
1900287
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

形狀

liquid

折射率

n20/D 1.458 (lit.)

bp

69 °C (lit.)

密度

1.51 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

BrC1CC1

InChI

1S/C3H5Br/c4-3-1-2-3/h3H,1-2H2

InChI 密鑰

LKXYJYDRLBPHRS-UHFFFAOYSA-N

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一般說明

溴环丙烷是有机合成的关键中间体,也是药物开发中构建多种化学结构的基础材料。

象形圖

Flame

訊號詞

Danger

危險聲明

危險分類

Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

21.2 °F - closed cup

閃點(°C)

-6 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Mechanism-Driven Elaboration of an Enantioselective Bromocyclopropanation Reaction of Allylic Alcohols
S Taillemaud, et al.
Angewandte Chemie (International Edition in English), 127, 14314-14318 (2015)
John R Hornick et al.
Journal of experimental & clinical cancer research : CR, 31, 41-41 (2012-05-04)
Sigma-2 receptor ligands have been studied for treatment of pancreatic cancer because they are preferentially internalized by proliferating cells and induce apoptosis. This mechanism of apoptosis is poorly understood, with varying reports of caspase-3 dependence. We evaluated multiple sigma-2 receptor
Carmen Abate et al.
Journal of medicinal chemistry, 57(8), 3314-3323 (2014-04-05)
Despite the promising potentials of σ2 receptors in cancer therapy and diagnosis, there are still ambiguities related to the nature and physiological role of the σ2 protein. With the aim of providing potent and reliable tools to be used in
Carmen Abate et al.
ChemMedChem, 6(1), 73-80 (2010-11-12)
Many new chemotherapeutic agents are under preclinical investigation and, despite efforts to more selectively target cancer cells, limitations such as toxicity and inherent resistance are often encountered. Therefore, alternative strategies are needed to treat cancer and overcome such limitations. We
Mauro Niso et al.
ChemMedChem, 8(12), 2026-2035 (2013-10-10)
With the aim of contributing to the development of novel antitumor agents, high-affinity σ2 receptor agonists were developed, with 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline (15) and 9-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)butyl]-9H-carbazole (25) showing exceptional selectivity for the σ2 subtype. Most of the compounds displayed notable antiproliferative activity in

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