推荐产品
![1H-pyrrolo[3,2-c]pyridine AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/291/250/879d6f32-75bf-4a4a-a366-18cbd62dcc37/640/879d6f32-75bf-4a4a-a366-18cbd62dcc37.png)
![1H-Pyrrolo[2,3-c]pyridine AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/332/393/b23058ac-c477-42b5-9890-dc5c2af5cec7/640/b23058ac-c477-42b5-9890-dc5c2af5cec7.png)
![1H-pyrrolo[3,2-b]pyridine AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/276/658/7030377c-695d-4006-bbf3-fe99211bb7e7/640/7030377c-695d-4006-bbf3-fe99211bb7e7.png)
化驗
98%
形狀
solid
mp
105-107 °C (lit.)
SMILES 字串
c1cnc2[nH]ccc2c1
InChI
1S/C7H6N2/c1-2-6-3-5-9-7(6)8-4-1/h1-5H,(H,8,9)
InChI 密鑰
MVXVYAKCVDQRLW-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
應用
最新用于合成氮杂血清素的原料。
此杂环分子可用作药物结构单元
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
John J Caldwell et al.
Journal of medicinal chemistry, 51(7), 2147-2157 (2008-03-19)
Fragment-based screening identified 7-azaindole as a protein kinase B inhibitor scaffold. Fragment elaboration using iterative crystallography of inhibitor-PKA-PKB chimera complexes efficiently guided improvements in the potency and selectivity of the compounds, resulting in the identification of nanomolar 6-(piperidin-1-yl)purine, 4-(piperidin-1-yl)-7-azaindole, and
Pei-Wen Wu et al.
Journal of the American Chemical Society, 128(45), 14426-14427 (2006-11-09)
We report the synthesis of 3-(2-aminoethyl)-5-ol-1H-pyrrolo[2,3-b]pyridine (7-azaserotonin), which may potentially serve as an agonist or antagonist of serotonin receptors. In alcohols, the solvent (e.g., ethanol) catalyzed proton-transfer reaction takes place for 7-azaserotonin in the excited state, resulting in dual emission.
Xin Wang et al.
The Journal of organic chemistry, 71(10), 4021-4023 (2006-05-06)
A practical synthesis of a key pharmaceutical intermediate, 2-[(1H-pyrrolo[2,3-b]pyridine-4-yl)methylamino]-5-fluoronicotinic acid (1), is described. To introduce the aminomethyl moiety of 2 via a palladium-catalyzed cyanation/reduction sequence, a regioselective chlorination of 7-azaindole via the N-oxide was developed. A highly selective monodechlorination of
Alastair Donald et al.
Journal of medicinal chemistry, 50(10), 2289-2292 (2007-04-25)
6-phenylpurines were identified as novel, ATP-competitive inhibitors of protein kinase B (PKB/Akt) from a fragment-based screen and were rapidly progressed to potent compounds using iterative protein-ligand crystallography with a PKA-PKB chimeric protein. An elaborated lead compound showed cell growth inhibition
Bruno Aleksander Martek et al.
Drug testing and analysis, 11(4), 617-625 (2019-02-08)
The high frequency of the synthetic cannabinoid receptor agonists (SCRAs) emergence renders this group of new psychoactive compounds particularly demanding in terms of detection, identification, and responding. Without the available reference material, one of the specific problems is differentiation and
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门