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Merck

719889

Sigma-Aldrich

Resomer® RG 502,聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide 50:50, ester terminated, Mw 7,000-17,000

别名:

RESOMER® RG 502

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About This Item

线性分子式:
[C3H4O2]x[C2H2O2]y
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

amorphous

饋電比

lactide:glycolide 50:50

分子量

Mw 7,000-17,000

降解時間

<3 months

黏度

0.16-0.24 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

轉變溫度

Tg 42-46 °C

運輸包裝

wet ice

儲存溫度

2-8°C

應用

Resomer® RG 502可用于制备基于PLGA的纳米 药物递送系统,用于抗炎药物6-溴靛玉红-3′-甘油肟醚(6BIGOE)。

它还可用于制备盐酸纳洛酮递送的控制释放。

特點和優勢

  • 生物相容性
  • 生物可降解
  • 可加工成几乎任何形状和尺寸
  • 机械性能可调

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Elevated intraocular pressure (IOP) in glaucoma is due to impairment of aqueous humor drainage via the uveoscleral or trabecular outflow pathway. Latanoprost reduces IOP by increasing the uveoscleral outflow. Despite its potency, long-term daily application of it may cause undesirable
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International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
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Journal of the American College of Surgeons, 218(1), 102-107 (2013-11-12)
Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures
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To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies. Retrospective, interventional cohort study. All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital. Review and
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Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

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