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Merck

671576

Sigma-Aldrich

N-苯基羟胺

≥95.0%

别名:

N -羟基苯胺, N-羟基苯胺

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About This Item

经验公式(希尔记法):
C6H7NO
CAS号:
分子量:
109.13
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥95.0%

形狀

solid

mp

80-84 °C

儲存溫度

−20°C

SMILES 字串

ONc1ccccc1

InChI

1S/C6H7NO/c8-7-6-4-2-1-3-5-6/h1-5,7-8H

InChI 密鑰

CKRZKMFTZCFYGB-UHFFFAOYSA-N

應用

N-苯基羟胺作为起始材料,可用于下列合成反应:
  • 通过连续3,3-重排和环脱水反应,用金催化剂与脂肪族末端炔烃进行处理,合成2-烷基吲哚。
  • 通过三组分一锅催化法,与醛和 α, β不饱和醛合成异恶唑烷。
  • 通过homo3+2偶极环加成反应,处理醛和环丙烷,合成四氢1,2-恶嗪。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Au-catalyzed synthesis of 2-alkylindoles from N-arylhydroxylamines and terminal alkynes
Wang Y, et al.
Chemical Communications (Cambridge, England), 47(27), 7815-7817 (2011)
Copper-catalyzed amination of alkenes and ketones by phenylhydroxylamine.
Ho C-M and Lau T-C
New. J. Chem., 24(11), 859-863 (2000)
T P Bradshaw et al.
Free radical biology & medicine, 18(2), 279-285 (1995-02-01)
Previous studies have shown that incubation of rat red blood cells in vitro with phenylhydroxylamine (50-300 microM) induces rapid splenic sequestration of the red cells on reintroduction to isologous rats. EPR and the spin trapping agent, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), were utilized
Lloyd J Nadeau et al.
Applied and environmental microbiology, 69(5), 2786-2793 (2003-05-07)
Hydroxylamino aromatic compounds are converted to either the corresponding aminophenols or protocatechuate during the bacterial degradation of nitroaromatic compounds. The origin of the hydroxyl group of the products could be the substrate itself (intramolecular transfer mechanism) or the solvent water
C C Somerville et al.
Journal of bacteriology, 177(13), 3837-3842 (1995-07-01)
Pseudomonas pseudoalcaligenes JS45 grows on nitrobenzene as a sole source of carbon, nitrogen, and energy. The catabolic pathway involves reduction to hydroxylaminobenzene followed by rearrangement to o-amino-phenol and ring fission (S. F. Nishino and J. C. Spain, Appl. Environ. Microbiol.

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