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Merck

193984

Sigma-Aldrich

1-甲基吲哚

≥97%

别名:

NSC 212534

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About This Item

经验公式(希尔记法):
C9H9N
CAS号:
分子量:
131.17
Beilstein:
111026
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥97%

形狀

liquid

折射率

n20/D 1.606 (lit.)

bp

133 °C/26 mmHg (lit.)

密度

1.051 g/mL at 20 °C (lit.)

SMILES 字串

Cn1ccc2ccccc12

InChI

1S/C9H9N/c1-10-7-6-8-4-2-3-5-9(8)10/h2-7H,1H3

InChI 密鑰

BLRHMMGNCXNXJL-UHFFFAOYSA-N

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一般說明

1-甲基吲哚在 Au (III)/TPPMS 催化下与苄基和苄基醇发生苄基化反应

應用

1-甲基吲哚被用于 1-甲基吲哚与 1-(2,4,6-三硝基苯基)丙-2-酮的电子给体-受体配合物的缔合常数的测定
制备用反应物:
  • 具有药物活性的 2-氧代-1-吡咯烷类似物
  • 非受体酪氨酸激酶(Src 激酶)抑制剂
  • 用于蛋白激酶 C (PKC) 成像的 PET 试剂
  • Ynediones 作为高活性 Michael 系统
  • 抗癌药
  • 吲哚类多环衍生物
  • 用于糖原合成酶激酶-3 (GSK-3) 成像的 PET 试剂
  • 抗朊病毒药物
  • 具有降血脂活性的双吲哚衍生物
  • PET 癌症显像剂

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Martin G Banwell et al.
Organic letters, 8(21), 4959-4961 (2006-10-06)
[reaction: see text] Reaction of N-methylindole (4) with 6,6-dibromobicyclo[3.1.0]hexane (5) in the presence of silver tetrafluoroborate affords conjugate 7 in 67% yield. This product can be readily elaborated to compounds 12b and 13b which embody the polycyclic frameworks associated with
Association constants for the electron-donor-acceptor complexes of indole and 1-methylindole with 1-(2, 4, 6-trinitrophenyl) propan-2-one from nuclear magnetic resonance shift measurements. An anomalous scatchard plot.
Chudek JA, et al.
J. Chem. Soc., Faraday, 84(4), 1145-1152 (1988)
Hongmei Liu et al.
Malaria journal, 17(1), 348-348 (2018-10-07)
Anopheles sinensis is an important vector for the spread of malaria in China. Olfactory-related behaviours, particularly oviposition site seeking, offer opportunities for disrupting the disease-transmission process. This is the first report of the identification and characterization of AsinOrco and AsinOR10
Nicholas R Deprez et al.
Journal of the American Chemical Society, 128(15), 4972-4973 (2006-04-13)
This communication describes the rational development of a PdII-catalyzed method for the direct 2-arylation of indoles using [Ar-IIII-Ar]BF4. These reactions proceed under remarkably mild conditions (often at room temperature and in the presence of ambient air and moisture), and these
Benjamin S Lane et al.
Journal of the American Chemical Society, 127(22), 8050-8057 (2005-06-02)
We have recently developed palladium-catalyzed methods for direct arylation of indoles (and other azoles) wherein high C-2 selectivity was observed for both free (NH)-indole and (NR)-indole. To provide a rationale for the observed selectivity ("nonelectrophilic" regioselectivity), mechanistic studies were conducted

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