推荐产品
product name
DL-脯氨酸, ReagentPlus®, 99%
產品線
ReagentPlus®
化驗
99%
形狀
powder
反應適用性
reaction type: solution phase peptide synthesis
mp
208 °C (dec.) (lit.)
應用
peptide synthesis
SMILES 字串
OC(=O)C1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI 密鑰
ONIBWKKTOPOVIA-UHFFFAOYSA-N
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一般說明
DL-脯氨酸,又名2-吡咯烷羧酸,是一种氨基酸,具有限制性phi( ϕ)角,常用作多肽固相合成的转角诱导分子。
應用
DL-脯氨酸可用于制备cis-氨基脯氨酸-烯烃(cis-Apa)连接分子,进一步用作液相法多肽合成环状伪肽的中间体。
法律資訊
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
cis-Apa: A practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage
The Journal of Organic Chemistry, 76, 766-772 (2011)
Recent Progress in Solid-Phase Total Synthesis of Naturally Occurring Small Peptides
Advanced Synthesis & Catalysis, 364, 1934-1961 (2022)
Cardiovascular diabetology, 13, 89-89 (2014-06-03)
Despite advances in the treatment of heart failure, mortality remains high, particularly in individuals with diabetes. Activated transforming growth factor beta (TGF-β) contributes to the pathogenesis of the fibrotic interstitium observed in diabetic cardiomyopathy. We hypothesized that high glucose enhances
The Journal of biological chemistry, 290(21), 13440-13453 (2015-04-04)
Lipid A in LPS activates innate immunity through the Toll-like receptor 4 (TLR4)-MD-2 complex on host cells. Variation in lipid A has significant consequences for TLR4 activation and thus may be a means by which Gram-negative bacteria modulate host immunity.
Molecular biology and evolution, 32(7), 1695-1707 (2015-03-10)
Although an increasing number of horizontal gene transfers have been reported in eukaryotes, experimental evidence for their adaptive value is lacking. Here, we report the recent transfer of a 158-kb genomic region between Torulaspora microellipsoides and Saccharomyces cerevisiae wine yeasts
Chromatograms
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