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Merck

133507

Sigma-Aldrich

2-氨基-5-硝基噻唑

97%

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About This Item

经验公式(希尔记法):
C3H3N3O2S
CAS号:
分子量:
145.14
Beilstein:
126797
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

solid

mp

195-200 °C (dec.) (lit.)

溶解度

95% ethanol: soluble 1g/150g at 20 °C
diethyl ether: soluble 1g/250g at 20 °C
chloroform: insoluble
water: slightly soluble

SMILES 字串

Nc1ncc(s1)[N+]([O-])=O

InChI

1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5)

InChI 密鑰

MIHADVKEHAFNPG-UHFFFAOYSA-N

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一般說明

2-氨基-5-硝基噻唑(ANT)是一种缺氧放射增敏药物 。ANT通过甲醇中的钯形成平面正方形络合物,即反式-[PdCl2(ANT)2]

應用

2-氨基-5-硝基噻唑作为重氮组分用于合成单偶氮型分散染料 。在寡核苷酸和蛋白质的基质辅助激光解吸/电离飞行时间质谱研究中用作基质

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Analysis of Oligonucleotide and Protein via Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Using 2-Amino-5-nitrothiazole as an Effective Matrix [J].
ZHOU LH, et al.
Chemical Research in Chinese Universities, 12, 012-012 (2004)
Synthesis and Spectral Properties of Hetaryl Monoazo dyes derived from 2-amino-5-nitrothiazole.
OTUTU JO, et al.
Orient. J. Chem., 27(4), 2011-2011 (1389)
K A Skov et al.
Radiation research, 112(2), 273-282 (1987-11-01)
Complexes of general formula [PtCl2(NH3)L] with one radiosensitizing ligand per platinum are compared with ligand L alone, complexes with two radiosensitizers per platinum [PtCl2L2], and their analogs with NH3 ligands, with respect to radiosensitizing properties and toxicity in CHO cells.
Evaluation of 2-amino-5-nitrothiazole as a hypoxic cell radiosensitizer.
S Rockwell et al.
Radiation research, 90(3), 575-585 (1982-06-01)
2-amino-5-nitrothiazole.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 31, 71-77 (1983-07-01)

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