42643

(−)-Huperzine A

analytical standard

• Synonym(s): (−)-Selagine, Kimpukan A
• Empirical Formula (Hill Notation): C₁₅H₁₈N₂O
• CAS Number: 102518-79-6
• Molecular Weight: 242.32
• MDL number: MFCD01714949
• UNSPSC Code: 85151701
• PubChem Substance ID: 329756255
• NACRES: NA.24

Properties

• grade: analytical standard
• Assay: ≥98.0% (HPLC)
• optical activity: [α]/D -153±5°, c = 0.5 in methanol
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): food and beverages
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12CC3=C(C=CC(=O)N3)[C@@](N)(CC(C)=C1)C2=CC
• InChI: 1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1
• InChI key: ZRJBHWIHUMBLCN-YQEJDHNASA-N

Description

General description

(−)-Huperzine A, a sesquiterpene alkaloid isolated from the Chinese herb Huperzia serrata. Its mode of action involves the strong inhibition of acetylcholinesterase (AChE).

Application

(−)-Huperzine A may be used as a reference standard in the determination of the analyte in plasma samples using high-performance liquid chromatography (HPLC) with fluorescence detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330
• Precautionary Statements: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable