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  • Interlaboratory studies and initiatives developing standards for proteomics.

Interlaboratory studies and initiatives developing standards for proteomics.

Proteomics (2013-01-16)
Alexander R Ivanov, Christopher M Colangelo, Craig P Dufresne, David B Friedman, Kathryn S Lilley, Karl Mechtler, Brett S Phinney, Kristie L Rose, Paul A Rudnick, Brian C Searle, Scott A Shaffer, Susan T Weintraub
ABSTRACT

Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Proteomics Dynamic Range Standard Set, Protein Mass Spectrometry Calibration Standard
Sigma-Aldrich
MS PhosphoMix 1 Light, Phosphopeptide Standard for MS
Sigma-Aldrich
MS PhosphoMix 1 Heavy, Phosphopeptide Standard for MS
Sigma-Aldrich
Universal Proteomics Standard Set, Protein Mass Spectrometry Calibration Standard
Sigma-Aldrich
MS PhosphoMix 2 Light, Phosphopeptide Standard for MS
Sigma-Aldrich
MS PhosphoMix 3 Heavy, Phosphopeptide Standard for MS
Sigma-Aldrich
MS PhosphoMix 3 Light, Phosphopeptide Standard for MS
Sigma-Aldrich
MS PhosphoMix 2 Heavy, Phosphopeptide Standard for MS