- p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
Bioorganic & medicinal chemistry letters (2001-01-05)
A M Redman, J S Johnson, R Dally, S Swartz, H Wild, H Paulsen, Y Caringal, D Gunn, J Renick, M Osterhout, J Kingery-Wood, R A Smith, W Lee, J Dumas, S M Wilhelm, T J Housley, A Bhargava, G E Ranges, A Shrikhande, D Young, M Bombara, W J Scott
PMID11140741
ABSTRACT
Inhibitors of the MAP kinase p38 are potentially useful for the treatment for osteoporosis, arthritis, and other inflammatory diseases. A series of thienyl, furyl, and pyrrolyl ureas has been identified as potent p38 inhibitors, displaying in vitro activity in the nanomolar range.
MATERIALS
Product Number
Brand
Product Description
Pricing and availability is not currently available.