Skip to Content
Merck
All Photos(1)

Documents

M81209

Sigma-Aldrich

Methylsuccinic acid

99%

Synonym(s):

(±)-α-Methylsuccinic acid, (±)-2-Methylsuccinic acid, (±)-Methylsuccinic acid, 2-Methylbutane-1,4-dioic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
HO2CCH2CH(CH3)CO2H
CAS Number:
498-21-5
Molecular Weight:
132.11
Beilstein:
1722946
EC Number:
207-857-1
MDL number:
MFCD00002659
UNSPSC Code:
12352100
PubChem Substance ID:
24897223
NACRES:
NA.22

Assay

99%

form

crystals

mp

110-115 °C (lit.)

SMILES string

CC(CC(O)=O)C(O)=O

InChI

1S/C5H8O4/c1-3(5(8)9)2-4(6)7/h3H,2H2,1H3,(H,6,7)(H,8,9)

InChI key

WXUAQHNMJWJLTG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Glutaconic acid 97% (T)

Sigma-Aldrich

49360

Glutaconic acid

3-Methylglutaric acid 99%

Sigma-Aldrich

M47604

3-Methylglutaric acid

J A Montgomery et al.
The Biochemical journal, 214(2), 641-644 (1983-08-15)
Rats excrete increased ethylmalonate and methylsuccinate when given ethylmalonate in the diet; when given methylsuccinate they excrete methylsuccinate and mesaconate. Tenfold more labelled mesaconate was produced from threo-methyl[2,3-2H2] succinate precursor than from the erythro isomer. Our findings suggest trans-dehydrogenation of
M J Nowaczyk et al.
Metabolism: clinical and experimental, 47(7), 836-839 (1998-07-17)
Ethylmalonic encephalopathy (EE), an organic aciduria of unknown etiology characterized by developmental delay, hypotonia, and vascular instability associated with lactic acidemia and urinary excretion of ethylmalonic acid (EMA) and methylsuccinic acid (MSA), has been described in 11 patients. To test
Christopher J R Illingworth et al.
The journal of physical chemistry. A, 110(20), 6487-6497 (2006-05-19)
We have presented a method for modeling polarization in hybrid QM/MM calculations. The method, which expresses the induced dipoles as a set of "induced" charges, is based on the induced dipole approach and methodology for calculating potential-derived point charges from
B A Amendt et al.
The Journal of clinical investigation, 79(5), 1303-1309 (1987-05-01)
We describe two patients with short-chain acyl-coenzyme A (CoA) dehydrogenase (SCADH) deficiency. Neonate I excreted large amounts of ethylmalonate and methylsuccinate; ethylmalonate excretion increased after a medium-chain triglyceride load. Neonate II died postnatally and excreted ethylmalonate, butyrate, 3-hydroxybutyrate, adipate, and
M J Nowaczyk et al.
American journal of medical genetics, 75(3), 292-296 (1998-02-25)
Central nervous system malformations have been reported in a number of inherited enzyme defects. Ethylmalonic encephalopathy, an organic aciduria of unknown pathogenesis, has not been reported previously in association with brain or spinal cord malformations. We report on 2 sibs
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service