SAB3500141

Anti-TRESK antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-KCNK18, Anti-Potassium channel subfamily K member 18, Anti-TRESK2, Anti-TRIK
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, rat, mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI accession no.: NP_862823
• UniProt accession no.: Q7Z418
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KCNK18(338567)

Description

General description

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3.

Immunogen

TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.

Biochem/physiol Actions

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K⁺ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura.

Features and Benefits

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Linkage

The action of this antibody can be blocked using blocking peptide SBP3500141.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable