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D0565

Sigma-Aldrich

Digoxin-BSA bovine

lyophilized powder

Synonym(s):

Digoxin-BSA

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

bovine

form

lyophilized powder

extent of labeling

~10 mol Digoxin per mol albumin

technique(s)

inhibition assay: suitable

UniProt accession no.

storage temp.

2-8°C

Gene Information

cow ... ALB(280717)

Application

Digoxin-BSA bovine is a cardioactive glycoside which can increase intracellular calcium concentration through Na+/K+-ATPase pump inhibition. Digoxin has been used in treatments of heart related disease and also studies of cancer treatments. It has shown the ability to inhibit prostate cancer cell growth, but has also shown a reduction in the efficiency of chemotherapy (reduced drug absorption) by increasing the amount of P-glycoprotein (Pgp).

Biochem/physiol Actions

Antigen-protein conjugate.

Physical form

Lyophilized from 0.06 M Tris

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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