94370

Uridine 5′-triphosphate trisodium salt dihydrate

≥80%

• Synonym(s): UTP
• Linear Formula: C₉H₁₂N₂O₁₅P₃Na₃
• CAS Number: 116295-90-0
• Molecular Weight: 586.12
• Beilstein: 3585234
• EC Number: 243-347-5
• MDL number: MFCD00150714
• UNSPSC Code: 41106305
• PubChem Substance ID: 57653602
• NACRES: NA.51

Properties

• Assay: ≥80%
• form: powder
• impurities: ≤15% UDP; ≤5% UMP
• mp: >140 °C (dec.) (lit.)
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[Na+].[H]O[H].[H]O[H].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na.2H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;;2*1H2/q;3*+1;;/p-3/t4-,6-,7-,8-;;;;;/m1...../s1
• InChI key: KIYVKLDQLQZXKH-GTIFRNKBSA-K
• Gene Information: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Description

Application

Uridine 5′-diphosphate (UDP) and Uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).

Biochem/physiol Actions

P2Y receptor agonist.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves