Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

M0505

Sigma-Aldrich

Methylamine hydrochloride

≥98%

Synonym(s):

Methanaminium chloride, Methylamine monohydrochloride, Methylammonium chloride, Monomethylammonium chloride

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
CH3NH2 · HCl
CAS Number:
593-51-1
Molecular Weight:
67.52
Beilstein:
3588822
EC Number:
209-795-0
MDL number:
MFCD00012849
UNSPSC Code:
12352100
PubChem Substance ID:
57654342
NACRES:
NA.22

Assay

≥98%

form

powder or crystals

bp

225-230 °C/15 mmHg (lit.)

mp

231-233 °C (lit.)

solubility

H2O: 1 g in 10 mL, clear, colorless

SMILES string

Cl[H].CN

InChI

1S/CH5N.ClH/c1-2;/h2H2,1H3;1H

InChI key

NQMRYBIKMRVZLB-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Methylamine hydrochloride is used as a buildingblock for the synthesis of various organic compounds.

Application

Methylamine hydrochloride can be used as a reactant to synthesize:
  • Betahistine via aza-Michael reaction with 2-vinylpyridine in water.
  • Azatripyrrolic and azatetrapyrrolic macrocycles by reacting with pyrrole and formaldehyde via base-catalyzed Mannich reaction.
  • Tetrahydropyridines via Aza-Diels–Alder reaction with dienes and aldehydes.
  • N-methylsecondary arylamines from aryl chlorides via nickel-catalyzed amination reaction.

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

408.7 °F - closed cup

Flash Point(C)

209.3 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Trimethylamine hydrochloride analytical standard

Supelco

41284

Trimethylamine hydrochloride

Jixian Xu et al.
Science (New York, N.Y.), 367(6482), 1097-1104 (2020-03-07)
Wide-band gap metal halide perovskites are promising semiconductors to pair with silicon in tandem solar cells to pursue the goal of achieving power conversion efficiency (PCE) greater than 30% at low cost. However, wide-band gap perovskite solar cells have been
Thomas S Hofer et al.
Molecular bioSystems, 8(11), 2891-2900 (2012-08-01)
Molecular dynamics simulations have been performed to investigate the binding of tris(hydroxymethyl)-aminomethane to the surface of the core domain of the mouse cellular tumor antigen p53 employing the GROMOS and 53A6 force field parameter sets. A close investigation of the
Michaela Frybortova et al.
Journal of inorganic biochemistry, 126, 46-54 (2013-06-19)
In order to shed light on the mechanism that underlies activity of bifunctional mononuclear Pt(II) analogs of transplatin we examined in the present work a DNA binding mode of the analog of transplatin, namely trans-[Pt(CH3NH2)2Cl2], in which NH3 groups were
Jing-Jing Fang et al.
Waste management (New York, N.Y.), 32(7), 1401-1410 (2012-04-07)
This study investigated the odor compounds from different areas in a landfill site, which included the municipal solid waste (MSW)-related area, the leachate-related area and the sludge-related area. Nine sampling points were placed and 35 types of odorous substances were
Nicolas Fleury-Brégeot et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(31), 9564-9570 (2012-07-07)
Ammoniomethyl trifluoroborates are very powerful reagents that can be used to access biologically relevant aryl- and heteroaryl-methylamine motifs via Suzuki-Miyaura cross-couplings. Until now, this method was limited to the production of tertiary and primary amines. The synthesis of a large
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service