156159

Sodium cyanoborohydride

reagent grade, 95%

• Synonym(s): Sodium cyanotrihydridoborate
• Linear Formula: NaBH₃CN
• CAS Number: 25895-60-7
• Molecular Weight: 62.84
• Beilstein: 4152656
• EC Number: 247-317-2
• MDL number: MFCD00003516
• UNSPSC Code: 12352306
• PubChem Substance ID: 24849595
• NACRES: NA.22

Properties

• grade: reagent grade
• Assay: 95%
• form: powder
• reaction suitability: reagent type: reductant
• mp: >242 °C (dec.) (lit.)
• SMILES string: [Na+].[BH3-]C#N
• InChI: 1S/CH3BN.Na/c2-1-3;/h2H3;/q-1;+1
• InChI key: CVDUGUOQTVTBJH-UHFFFAOYSA-N

Description

General description

Sodium cyanoborohydride, also known as sodium cyanotrihydridoborate, is a mild reducing agent that is stable in acidic conditions. It is widely used in the selective reduction of aryl aldehydes and ketones.

Application

Reagent for selective reductions.

Sodium cyanoborohydride is used as a reagent: 

• To convert the amino-functional Si₃N₄ surface to a reactive surface with aldehyde groups.
• For coupling amino-modified oligonucleotide probes.
• In the synthesis of a novel phenolate-bridged dilanthanum(III) complex of interest as a model for metalloproteins.
• In the reductive amination of aldehydes and ketones, and in the reductive alkylation of amines.

Safety Information

• Pictograms: GHS02,GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H228,H260,H300 + H310 + H330,H314,H410
• Precautionary Statements: P210 - P231 + P232 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Skin Corr. 1B - Water-react 1
• Supplementary Hazards: EUH032
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 3
• Flash Point(F): 158.0 °F - closed cup
• Flash Point(C): 70 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves