G005750
HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide
application for HPLC
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About This Item
technique(s)
HPLC: suitable
test parameters
column: Ascentis Express RP-Amide, 10 cm x 2.1 mm I.D., 2.7 μm particles (53913-U)
mobile phase: [A] 20 mM ammonium formate in 50:50 (v/v) water:acetonitrile
flow rate: 0.6 mL/min
column temp.: 35 °C
detector: ESI(+), m/z 100-600
injection: 1 μL
suitability
application for HPLC
application(s)
clinical
Analysis Note
This application demonstrates the suitability of the Ascentis Express RP Amide for the analysis of CYP3A Inhibitors.
Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Analyte
Description
Ketoconazole
Mevinolin from Aspergillus sp.
analytical column
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mobile phase component
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standard
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