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259268

Sigma-Aldrich

Hexaethylene glycol

97%, average MN 300

Synonym(s):

Polyethylene glycol, 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol

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About This Item

Linear Formula:
H(OCH2CH2)6OH
CAS Number:
2615-15-8
Molecular Weight:
282.33
Beilstein:
1638281
EC Number:
220-045-1
MDL number:
MFCD00002877
UNSPSC Code:
12162002
PubChem Substance ID:
24855697
NACRES:
NA.23

product name

Hexaethylene glycol, 97%

Assay

97%

form

liquid

mol wt

average Mn 300

refractive index

n20/D 1.465 (lit.)

bp

217 °C/4 mmHg (lit.)

mp

5-7 °C (lit.)

density

1.127 g/mL at 25 °C (lit.)

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

OCCOCCOCCOCCOCCOCCO

InChI

1S/C12H26O7/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h13-14H,1-12H2

InChI key

IIRDTKBZINWQAW-UHFFFAOYSA-N

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Related Categories

Application

Substrate employed in the synthesis of binaphthol-based macrocyclic ethers using intramolecular oxidative coupling with CuCl(OH)-TMEDA.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Durand et al.
Biochemistry, 35(28), 9133-9139 (1996-07-16)
The interaction of the minor groove binding drug distamycin with the T-A-T triple helix and the A-T double helix was studied using circular dichroism spectroscopy and thermal denaturation. The triple helix was made by the oligonucleotide (dA)12-x-(dT)12-x-(dT)12, where x is
Pavel Vorobjev et al.
Nucleosides, nucleotides & nucleic acids, 23(6-7), 1047-1051 (2004-11-25)
New conjugates of bleomycin A5 with oligonucleotides are synthesized. The bleomycin residue was attached to the 3'- or 5'- terminus of hexadecathymidilate via a hexaethylene glycol phosphate linker. Newly designed conjugates were shown to cleave site-specifically both strands of a
Ewelina Burakowska et al.
Small (Weinheim an der Bergstrasse, Germany), 5(19), 2199-2204 (2009-07-03)
A convenient methodology for the synthesis of photolabile crosslinked hyperbranched polyglycerol nanocapsules is presented. These nanocarriers selectively and efficiently bind ionic guest molecules. The stability of the host-guest complexes formed depends on the counterion of the guest molecules. Moreover, the
O Bornet et al.
Journal of biomolecular NMR, 4(4), 575-580 (1994-07-01)
We present NMR studies of an intramolecular triple helix, the three strands of which have been linked by a hexaethylene glycol chain. To overcome the generally encountered difficulties of assignment in the homo-pyrimidine strands, the carbon Cl' of the pyrimidines
Xin Li et al.
Analytical chemistry, 84(6), 2609-2613 (2012-03-03)
Lipophilicity of chemicals and drug candidates is normally described in terms of octanol/water partitioning and log P. We investigated an alternate approach to lipophilicity determination using a mimic of an alkyl alcohol with compound partitioning quantified using acoustic sensing. A
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Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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