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  • [Effect of mefenamic acid and sodium salicylate on lymphocyte transformation due to phytohemagglutinin].

[Effect of mefenamic acid and sodium salicylate on lymphocyte transformation due to phytohemagglutinin].

Farmakologiia i toksikologiia (1980-03-01)
I V Petrova, G M Aleksandrova
ABSTRACT

It is established in in-vitro experiments that mefenamic acid and sodium salicylate inhibit to an equal measure the cell immunity test, a reaction of blast transformation of lymphocytes. The effect increases with the higher concentration of the drugs under study and depends on the time they are introduced into the culture with respect to the introduction of the non-specific mitotic stimulant phytohemagglutinin.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Mefenamic acid
Sigma-Aldrich
Sodium salicylate, 98.0-102.0% anhydrous basis, meets USP testing specifications
Sigma-Aldrich
Sodium salicylate, ≥99.5% (HPLC), puriss. p.a.
Sigma-Aldrich
Sodium salicylate, ReagentPlus®, ≥99.5% (titration)
Sigma-Aldrich
Sodium salicylate, puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)
Sodium salicylate, European Pharmacopoeia (EP) Reference Standard
Mefenamic acid, European Pharmacopoeia (EP) Reference Standard
Supelco
Mefenamic acid, analytical standard