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LM2000

Avanti

Sphingosine (d17:1)

Avanti Research™ - A Croda Brand LM2000, ethanol solution

Synonym(s):

heptadeca-sphing-4-enine

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About This Item

Empirical Formula (Hill Notation):
C17H35NO2
CAS Number:
6918-48-5
Molecular Weight:
285.47
UNSPSC Code:
12352211
NACRES:
NA.25

form

ethanol solution

packaging

pkg of 1 × 1 mL (LM2000-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM2000

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCC

InChI

1S/C17H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h13-14,16-17,19-20H,2-12,15,18H2,1H3/b14-13+/t16-,17+/m0/s1

InChI key

RBEJCQPPFCKTRZ-LHMZYYNSSA-N

Application

Sphingosine (d17:1) or heptadeca-sphing-4-enine might be used as an internal standard for the identification of long chain bases (LCBs) in Colletotrichum gloeosporioides mycelia. It is also used as an internal standard for sample preparation and LC-MS/MS analysis for sphingolipids.

Packaging

2 mL Amber Glass Sealed Ampule (LM2000-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

55.4 °F - closed cup

Flash Point(C)

13.0 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christopher M Adams et al.
The Journal of biological chemistry, 279(50), 52772-52780 (2004-09-29)
The current paper demonstrates that cholesterol and its hydroxylated derivative, 25-hydroxycholesterol (25-HC), inhibit cholesterol synthesis by two different mechanisms, both involving the proteins that control sterol regulatory element-binding proteins (SREBPs), membrane-bound transcription factors that activate genes encoding enzymes of lipid
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Frontiers in microbiology, 10, 1016-1016 (2019-06-06)
Fungal glucosylceramide plays important role in cell division, hyphal formation and growth, spore germination and the modulation of virulence and has recently been considered as target for small molecule inhibitors. In this study, we characterized CgGCS, a protein encoding a
Veera Venkata Ratnam Bandaru et al.
BMC neuroscience, 15, 137-137 (2014-12-30)
Cholesterol metabolism is important for the maintenance of myelin and neuronal membranes in the central nervous system. Blood concentrations of the brain specific cholesterol metabolite 24S-hydroxysterol to the peripheral metabolite 27-hydroxycholesterol may be useful surrogate markers for neurodegenerative diseases including
Claudia Rossi et al.
International journal of molecular sciences, 19(11) (2018-11-18)
Multiple sclerosis (MuS) is an autoimmune disease of the central nervous system characterized by neuroinflammation, neurodegeneration, and degradation of the myelin sheath. Epidemiological studies have shown that the female gender is more susceptible than the male gender to MuS development
Siker Kimbung et al.
Endocrine-related cancer, 24(7), 339-349 (2017-04-27)
The impact of systemic 27-hydroxycholesterol (27HC) and intratumoral CYP27A1 expression on pathobiology and clinical response to statins in breast cancer needs clarification. 27HC is an oxysterol produced from cholesterol by the monooxygenase CYP27A1, which regulates intracellular cholesterol homeostasis. 27HC also
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