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Key Documents

860417

Sigma-Aldrich

Salicylamide

99%

Synonym(s):

2-Hydroxybenzamide

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About This Item

Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
Beilstein:
742439
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

solid

mp

140-144 °C (lit.)

SMILES string

NC(=O)c1ccccc1O

InChI

1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)

InChI key

SKZKKFZAGNVIMN-UHFFFAOYSA-N

Gene Information

human ... AR(367)

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General description

Salicylamide is used as a starting material for synthesizing substituted salicylamides through acylation reactions.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Patricia D Sauzem et al.
European journal of medicinal chemistry, 43(6), 1237-1247 (2007-09-25)
In this work, we reported the synthesis and evaluation of the analgesic and anti-inflammatory properties of novel 3- or 4-substituted 5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-1-carboxyamidepyrazoles (where 3-/4-substituent=H/H, Me/H, Et/H, Pr/H, i-Pr/H, Bu/H, t-Bu/H, Ph/H, 4-Br-Ph/H and H/Me) designed in the exploration of the bioisosteric
Jessica Nilsson et al.
Journal of inorganic biochemistry, 105(12), 1795-1800 (2011-11-08)
Reaction of N-(2-hydroxybenzyl)-N-(2-picolyl) glycine (H(2)papy) with VOSO(4) in water gives the oxidovanadium(V) oxido-bridged dimer [{(papy)(VO)}(2) μ-O)] (1). Similarly, reaction of N-(2-hydroxybenzyl) glycine (H(2)glysal) with VOSO(4) gives [(glysal)VO(H(2)O)] (2) and reaction of salicylamide (Hsalam) with VOSO(4) in methanol gives [(salam)(2)VO] (3).
Peter L D Wildfong et al.
Journal of pharmaceutical sciences, 95(12), 2645-2656 (2006-08-23)
The potential for various small molecule organic crystals to undergo complete mechanically induced disordering is investigated. A model is proposed, which considers changes in free energy required for lattice incorporation of a critical dislocation density. Application requires knowledge of a
Yong-Jiang Zhao et al.
International journal of pharmaceutics, 379(1), 90-99 (2009-06-23)
Poly (ethylene glycol)s (PEGs) are potential drug carriers for improving the therapeutic index of anticancer agents. In this work, a novel methodology for constructing PEG prodrug of anthracycline anticancer drugs was developed based on N-Mannich base of salicylamide and its
Zenei Taira et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 803-807 (2004-03-30)
To elucidate the effects of Sho-saiko-to extract and its components, baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, against the effects of longer periods of acute hepatic injury induced by CCl4, we measured serum ALT activity in male Wistar rats for five

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