Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

D5946

Sigma-Aldrich

PD 150606

≥97% (HPLC)

Synonym(s):

(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H7IO2S
CAS Number:
179528-45-1
Molecular Weight:
306.12
MDL number:
MFCD00949076
UNSPSC Code:
12352200
PubChem Substance ID:
329798817
NACRES:
NA.77

Quality Level

100

Assay

≥97% (HPLC)

form

powder

storage condition

protect from light

color

yellowish

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

SMILES string

OC(=O)\C(S)=C\c1ccc(I)cc1

InChI

1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-

InChI key

DJCVSFWGKYHMKH-YVMONPNESA-N

Biochem/physiol Actions

PD 150606 is a selective; cell-permeable; non-peptide; uncompetitive calpain inhibitor.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H301,H315,H317,H318,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Necrostatin-1 ≥98% (HPLC)

Sigma-Aldrich

N9037

Necrostatin-1

ALLN Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM).

Sigma-Aldrich

208719

ALLN

Ac-YVAD-cmk ≥95% (HPLC)

Sigma-Aldrich

SML0429

Ac-YVAD-cmk

Shuchen Hsieh et al.
Journal of nanoscience and nanotechnology, 9(5), 2894-2901 (2009-05-21)
Aminopropylsilatrane (AP-silatrane) was investigated as an adhesive layer for anchoring Au nanoparticles on silicon substrates. We compared the preparation procedure and film quality of the AP-silatrane films to those of 3-aminopropyltriethoxysilane (APTES), which is commonly used for nanoparticle attachment on
Hong Wang et al.
Journal of inorganic biochemistry, 172, 16-22 (2017-04-19)
Calcium, as a ubiquitous second messenger, governs a large array of cellular processes and is necessary for cell survival. More recently, it was observed that the cytosolic Ca
Chinky Shiu Chen Liu et al.
eLife, 12 (2024-02-23)
T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues depends on
Lifeng Feng et al.
Clinical and translational medicine, 11(10), e587-e587 (2021-10-29)
Chemoresistance remains a major obstacle to successful cancer therapy, especially for advanced cancers. It used to be recognised as a stable outcome resulting from genetic changes. However, recent studies showed that chemoresistance can also be unstable and reversible with the
Elina Välimäki et al.
Journal of immunology (Baltimore, Md. : 1950), 197(8), 3315-3325 (2016-09-18)
Extracellular ATP is an endogenous danger signal that is known to activate inflammatory responses in innate immune cells, including macrophages. Activated macrophages start to secrete proteins to induce an immune response, as well as to recruit other immune cells to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service