850166P

18:0-20:4 PI(3,4,5)P3

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

• Synonym(s): 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-3,4,5-trisphosphate] (ammonium salt); PIP3[3′,4′,5′](18:0/20:4(5Z,8Z,11Z,14Z))
• Empirical Formula (Hill Notation): C₄₇H₉₈N₄O₂₂P₄
• CAS Number: 799268-60-3
• Molecular Weight: 1195.19
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850166P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850166P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850166P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]

Description

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:0-20:4 PI(3,4,5)P3 or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt) has been used in:

• liposomes for liposome-pelleting assay to identify the binding preference of FCH and double SH3 domains protein (FCHSD2) for specific phosphoinositide
• liposomes to study specific protein-lipid interactions
• host 1-O-1-(Z)-octadecenyl-2-arachidonoyl-sn-glycero-3-phosphocholine (plasmenyl-SAPC) small unilamellar vesicles (SUVs) in the presence of H₂O₂ to activate cyt c plasmalogenase activity

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850166P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850166P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids